Browsing Biomedical Sciences by Title
Now showing items 491-510 of 712
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An Overview of Nanoparticle Protein Corona Literature
( Wiley-Blackwell , 2023 , Article)The protein corona forms spontaneously on nanoparticle surfaces when nanomaterials are introduced into any biological system/fluid. Reliable characterization of the protein corona is, therefore, a vital step in the development ... -
Oxidative stress cytotoxicity induced by platinum-doped magnesia nanoparticles in cancer cells
( Elsevier , 2021 , Article)The aim of this study was to prepare, characterize, and determine the in vitro anticancer effects of platinum-doped magnesia (Pt/MgO) nanoparticles. The chemical compositions, functional groups, and size of nanoparticles ... -
Oxidative stress-induced Akt downregulation mediates green tea toxicity towards prostate cancer cells
( Elsevier , 2017 , Article)Green tea consumption has been shown to possess cancer chemopreventive activity. Polyphenol E (PE) is a widely used standardized green tea extract formulation. This study was designed to investigate the impact of PE on ... -
Oxidative Stress-Induced Endothelial Dysfunction in Cardiovascular Diseases
( IMR Press , 2022 , Article Review)Cardiovascular disease (CVD) is a major cause of mortality worldwide. A better understanding of the mechanisms underlying CVD is key for better management or prevention. Oxidative stress has been strongly implicated in the ... -
P3. 210 Estimating the antibody prevalence of herpes simplex virus type 2 among select middle east and north africa populations
( BMJ Publishing Group , 2017 , Conference Proceedings)Introduction There are very limited data on herpes simplex virus type 2 (HSV-2) infection in the Middle East and North Africa (MENA). We examined the overall and age-specific HSV-2 antibody prevalence among select MENA ... -
Pathogenic Homocystinuria-Associated T236N Mutation Dramatically Alters the Biochemical Properties of Cystathionine Beta-Synthase Protein
( MDPI , 2024 , Article)Background: Cystathione beta-synthase (CBS) T236N is a novel mutation associated with pyridoxine non-responsiveness, which presents a significant difficulty in the medical treatment of homocystinuria. Reported severe ... -
Performance Analysis of DCT and DWT Algorithms in Image Steganography
( Qatar University Press , 2021 , Poster)Frequency domain techniques such as Discrete Cosine Transform (DCT) and Discrete Wavelet Transform (DWT) ensures high accuracy when compared with the spatial domain techniques. Therefore, these image steganographic methods ... -
Performance evaluation of five commercial assays in assessing seroprevalence of HEV antibodies among blood donors
( Microbiology Society , 2018 , Article)Although hepatitis E virus (HEV) is mainly transmitted via the faecal-oral route, the rate of HEV transmission via blood donation is on the rise. However, the seroprevalence of HEV among blood donors is not well established ... -
Performance evaluation of five ELISA kits for detecting anti-SARS-COV-2 IgG antibodies
( Elsevier , 2020 , Article)ObjectivesTo evaluate and compare the performances of five commercial ELISA assays (EDI, AnshLabs, Dia.Pro, NovaTec, and Lionex) for detecting anti-SARS-CoV-2 IgG. Methods70 negative control samples (collected before the ... -
Performance evaluation of four type-specific commercial assays for detection of herpes simplex virus type 1 antibodies in a Middle East and North Africa population.
( Elsevier , 2018 , Article)The number of diagnostic assays for the detection of herpes simplex virus type 1 (HSV-1) antibodies has increased over the years. However, their performance characteristics could vary among global populations. To investigate ... -
Performance evaluation of novel fluorescent-based lateral flow immunoassay (LFIA) for rapid detection and quantification of total anti-SARS-CoV-2 S-RBD binding antibodies in infected individuals
( Elsevier , 2022 , Article)The vast majority of the commercially available LFIA is used to detect SARS-CoV-2 antibodies qualitatively. Recently, a novel fluorescence-based LIFA test was developed for quantitative measurement of the total binding ... -
Performance of Four Diagnostic Assays for Detecting Herpes Simplex Virus Type 2 Antibodies in the Middle East and North Africa
( Elsevier , 2019 , Article)Background Assessments of commercial assays in detecting herpes simplex virus type 2 (HSV-2) antibodies have shown variable sensitivity and specificity, and variation in performance by global population. Objective To ... -
Pfizer-BioNTech mRNA BNT162b2 Covid-19 vaccine protection against variants of concern after one versus two doses.
( Oxford University Press , 2021 , Article)Strategies for rolling out vaccination against Coronavirus Disease 2019 (Covid-19) varied across countries. A key question is whether delaying administration of the second vaccine dose to vaccinate the largest number of ... -
Physicochemical characterization and cancer cell antiproliferative effect of silver-doped magnesia nanoparticles
( Elsevier , 2023 , Article)Silver-doped magnesia nanoparticles (Ag/MgO) were synthesized using the precipitation method and characterized by various techniques such as X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), thermal ... -
Physicochemical characterization and cancer cell antiproliferative effect of silver-doped magnesia nanoparticles
( Elsevier , 2023 , Article)Silver-doped magnesia nanoparticles (Ag/MgO) were synthesized using the precipitation method and characterized by various techniques such as X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), thermal ... -
Physiological Changes and Interactions Between Microbiome and the Host During Pregnancy
( Frontiers Media , 2022 , Article Review)In recent years, it has become clear that microbiome play a variety of essential roles in human metabolism, immunity, and overall health and that the composition of these microbiome is influenced by our environment, diet, ... -
A pilot study on metabolic syndrome and its associated features among Qatari schoolchildren
( Dove Medical Press , 2011 , Article)Aim: This pilot study aimed to evaluate the individual features of the metabolic syndrome (MeS) and its frequency in Qatari schoolchildren aged 6-12 years. Background: MeS has a strong future risk for development of diabetes ... -
Plasmonic MXene-based nanocomposites exhibiting photothermal therapeutic effects with lower acute toxicity than pure MXene
( DOVE Medical Press , 2019 , Article)Purpose: Here, we fabricated two plasmonic 2D Ti3C2Tx-based nanocomposites (Au/MXene and Au/Fe3O4/MXene) with similarly high anti-cancer photothermal therapy (PTT) capabilities, but with less in vivo toxicity than a pure ... -
Platelets as a Possible Reservoir of HCV And Predictor of Response to Treatment
( SciTechnol , 2016 , Article)In the era of new Hepatitis C Virus (HCV) therapy, and the detection of extrahepatic HCV reservoirs such as peripheral blood mononuclear cells and platelets, it is important to understand the factors underlying resistance ... -
The polymorphism at the microRNA-155 binding site in AGTR1 gene is not significantly associated with rheumatic heart disease in Saudi Arabia population
( Bentham Science Publishers , 2020 , Article)Rheumatic heart disease (RHD) remains a major cause of cardiovascular diseases and the most devastating effects are on children and young adults. RHD is caused due to the interaction between microbial, environmental, ...