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The Spectrum of Mutations of Homocystinuria in the MENA Region
(
MDPI
, 2020 , Article Review)
Homocystinuria is an inborn error of metabolism due to the deficiency in cystathionine beta-synthase (CBS) enzyme activity. It leads to the elevation of both homocysteine and methionine levels in the blood and urine. ...
Potential Adverse Effects of Resveratrol: A Literature Review.
(
MDPI
, 2020 , Article Review)
Due to its health benefits, resveratrol (RE) is one of the most researched natural polyphenols. Resveratrol's health benefits were first highlighted in the early 1990s in the French paradox study, which opened extensive ...
Molecular Mechanisms of Colon Cancer Progression and Metastasis: Recent Insights and Advancements.
(
MDPI
, 2020 , Article Review)
Colorectal cancer (CRC), the third most common type of cancer, is the second leading cause of cancer-related mortality rates worldwide. Although modern research was able to shed light on the pathogenesis of CRC and provide ...
Novel therapeutic strategies for spinal osteosarcomas
(
Elsevier
, 2020 , Article Review)
At the dawn of the third millennium, cancer has become the bane of twenty-first century man, and remains a predominant public health burden, affecting welfare and life expectancy globally. Spinal osteogenic sarcoma, a ...
Advances in Cardiovascular Biomarker Discovery.
(
MDPI
, 2020 , Article Review)
Cardiovascular diseases are the leading causes of mortality worldwide. Among them, hypertension and its pathological complications pose a major risk for the development of other cardiovascular diseases, including heart ...
Vitamin D Signaling in Inflammation and Cancer: Molecular Mechanisms and Therapeutic Implications
(
MDPI
, 2020 , Article Review)
Vitamin D and its active metabolites are important nutrients for human skeletal health. UV irradiation of skin converts 7-dehydrocholesterol into vitamin D3, which metabolized in the liver and kidneys into its active form, ...
Severe acute respiratory syndrome coronavirus-2 natural animal reservoirs and experimental models: systematic review.
(
John Wiley and Sons
, 2020 , Article Review)
The current severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) outbreak has been rapidly spreading worldwide, causing serious global concern. The role that animal hosts play in disease transmission is still ...
Role of non-coding RNA networks in leukemia progression, metastasis and drug resistance.
(
BMC
, 2020 , Article Review)
Early-stage detection of leukemia is a critical determinant for successful treatment of the disease and can increase the survival rate of leukemia patients. The factors limiting the current screening approaches to leukemia ...
D-Dimer Concentrations and COVID-19 Severity: A Systematic Review and Meta-Analysis
(
Frontiers Media
, 2020 , Article Review)
Coronavirus disease 2019 (COVID-19) is a recently described infectious disease caused
by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Since late 2019,
COVID-19 has rapidly spread in virtually all countries, ...
The Microbiota and Gut-Related Disorders: Insights from Animal Models
(
MDPI
, 2020 , Article Review)
Over the past decade, the scientific committee has called for broadening our horizons in understanding host–microbe interactions and infectious disease progression. Owing to the fact that the human gut harbors trillions ...