Biomedical Sciences: المرسلات الحديثة

السجلات المعروضة 481 -- 500 من 809

    • Between Inflammation and Autophagy: The Role of Leptin-Adiponectin Axis in Cardiac Remodeling 

      Kamareddine, Layla; Ghantous, Crystal; Allouch, Soumaya; Al-Ashmar, Sara; Anlar, Gulsen; ... more authors ( Dove Medical Press , 2021 , Article Review)
      Cardiac remodeling is the process by which the heart adapts to stressful stimuli, such as hypertension and ischemia/reperfusion; it ultimately leads to heart failure upon long- term exposure. Autophagy, a cellular catabolic ...

    • The effect of surface-modified gold nanorods on the early stage of embryonic development and angiogenesis: Insight into the molecular pathways 

      Mahmoud, Nouf N.; Zakaria, Zain Zaki; Kheraldine, Hadeel; Gupta, Ishita; Vranic, Semir; ... more authors ( MDPI , 2021 , Article)
      Gold nanorods have been implicated in several biomedical applications. Herein, the effect of two surface-modified gold nanorods on the early stages of embryogenesis and angiogenesis was investigated using avian embryos at ...

    • COVID-19 Vaccine Platforms: Challenges and Safety Contemplations 

      Al-Jighefee, Hadeel; Najjar, Hoda; Ahmed, Muna; Qush, Abeer; Awwad, Sara; ... more authors ( MDPI , 2021 , Article Review)
      The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a pandemic as of March 2020, creating a global crisis and claiming millions of lives. To halt the pandemic and alleviate its impact on society, ...

    • Antibody Response to SARS-CoV-2: A Cohort Study in Qatar's Primary Care Settings. 

      Syed, Mohamed Ahmed; Al Nuaimi, Ahmed Sameer; Nasrallah, Gheyath K; Althani, Asmaa Ali J F; Zainel, Abduljaleel Abdullatif; ... more authors ( SAGE Publications , 2021 , Article)
      Globally, countries are rolling out Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) quarantine policies and vaccination programs. Research studies are needed in helping understand the likelihood of acquired ...

    • Waning of BNT162b2 Vaccine Protection against SARS-CoV-2 Infection in Qatar. 

      Chemaitelly, Hiam; Tang, Patrick; Hasan, Mohammad R; AlMukdad, Sawsan; Yassine, Hadi M; ... more authors ( Massachusetts Medical Society , 2021 , Article)
      Waning of vaccine protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection or coronavirus disease 2019 (Covid-19) is a concern. The persistence of BNT162b2 (Pfizer-BioNTech) vaccine ...

    • Epidemiological impact of prioritising SARS-CoV-2 vaccination by antibody status: Mathematical modelling analyses 

      Ayoub, H.H.; Ayoub, Houssein H.; Chemaitelly, Hiam; Makhoul, Monia; Al Kanaani, Zaina; ... more authors ( BMJ Publishing Group , 2021 , Article)
      Background Vaccines against SARS-CoV-2 have been developed, but their availability falls far short of global needs. This study aimed to investigate the impact of prioritising available doses on the basis of recipient ...

    • Pfizer-BioNTech mRNA BNT162b2 Covid-19 vaccine protection against variants of concern after one versus two doses. 

      Abu-Raddad, Laith J; Chemaitelly, Hiam; Yassine, Hadi M; Benslimane, Fatiha M; Al Khatib, Hebah A; ... more authors ( Oxford University Press , 2021 , Article)
      Strategies for rolling out vaccination against Coronavirus Disease 2019 (Covid-19) varied across countries. A key question is whether delaying administration of the second vaccine dose to vaccinate the largest number of ...

    • SARS-CoV-2 Infection Is at Herd Immunity in the Majority Segment of the Population of Qatar. 

      Al-Thani, Mohamed H; Farag, Elmoubasher; Bertollini, Roberto; Al Romaihi, Hamad Eid; Abdeen, Sami; ... more authors ( Oxford University Press , 2021 , Article)
      Qatar experienced a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemic that disproportionately affected the craft and manual worker (CMW) population, who comprise 60% of the total population. This study ...

    • SARS-CoV-2 antibody-positivity protects against reinfection for at least seven months with 95% efficacy 

      Laith J., Abu-Raddad; Chemaitelly, Hiam; Coyle, Peter; Malek, Joel A.; Ahmed, Ayeda A.; ... more authors ( Elsevier , 2021 , Article)
      Background Reinfection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been documented, raising public health concerns. SARS-CoV-2 reinfections were assessed in a cohort of antibody-positive persons ...

    • SARS-CoV-2 seroprevalence in the urban population of Qatar: An analysis of antibody testing on a sample of 112,941 individuals 

      Peter V., Coyle; Chemaitelly, Hiam; Ben Hadj Kacem, Mohamed Ali; Abdulla Al Molawi, Naema Hassan; El Kahlout, Reham Awni; ... more authors ( Elsevier , 2021 , Article)
      The study objective was to the assess level of detectable severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies in the urban population of Qatar. Antibody testing was performed on residual blood specimens ...

    • mRNA-1273 COVID-19 vaccine effectiveness against the B.1.1.7 and B.1.351 variants and severe COVID-19 disease in Qatar 

      Chemaitelly, Hiam; Yassine, Hadi M.; Benslimane, Fatiha M.; Al Khatib, Hebah A.; Tang, Patrick; ... more authors (2021 , Article)
      The SARS-CoV-2 pandemic continues to be a global health concern. The mRNA-1273 (Moderna) vaccine was reported to have an efficacy of 94.1% at preventing symptomatic COVID-19 due to infection with ‘wild-type’ variants in a ...

    • Performance Analysis of DCT and DWT Algorithms in Image Steganography 

      Najeeb, Al Anood; Maadeed, Somaya Al; Maadeed, Noor Al ( Qatar University Press , 2021 , Poster)
      Frequency domain techniques such as Discrete Cosine Transform (DCT) and Discrete Wavelet Transform (DWT) ensures high accuracy when compared with the spatial domain techniques. Therefore, these image steganographic methods ...

    • Elaeagnus Angustifolia extract inhabits cell invasion of human colorectal cancer cells and increases the survival rate of the Drosophila colon cancer model 

      Fouzat, Arij ( Qatar University Press , 2021 , Poster)
      Colorectal cancer (CRC), the third most common type of cancer in the world, is an aggressive type of cancer with high tendency to metastasize and invade to other tissues and distant organs. Traditional CRC treatment regimen ...

    • PROFILE OF OXIDATIVE STRESS GENES IN RESPONSE TO OBESITY TREATMENT 

      AHMED, AMIRA; FARAH, HUDA; Ahmed, Omnia; Elsayegh, Dina; ElGamal, Abdelrahman; ... more authors ( Qatar University Press , 2021 , Poster)
      Background: Oxidative stress (OS) is an imbalance between free radical production and the antioxidants defense in the body. Previous studies demonstrated the correlation of OS to the increased risk of developing metabolic ...

    • Ecotoxicological assessment of two surfactant on the emryonic development 

      Al-dosari, Aldana; Younes, Nadin; Nasrallah, Gheyath ( Qatar University Press , 2021 , Poster)
      In this study, zebrafish (Danio rerio) embryos was served as a model for marine fauna to determine if there is any potential of organ-specific toxicity (neuromuscular, hepatic, cytotoxic, and cardiac) caused by Silicone-Q-22 ...

    • Metagenomic Analysis of Oral Microbiome during pregnancy 

      Farah, Huda Mohamed; Elamin, Muram Elmubarak; Nader, Rahaf Nader Nader; Alabsi, Rana Said; Bouabidi, Salma Bouazza; ... more authors ( Qatar University Press , 2021 , Poster)
      Pregnancy is a dynamic physiological process associated with significant hormonal, immune and metabolic changes to support the growth and development of the fetus. Several studies have highlighted the role of gut microbiota ...

    • A Whole-Genome Sequencing Association Study of Low Bone Mineral Density Identifies New Susceptibility Loci in the Phase I Qatar Biobank Cohort 

      Younes, Nadin; Abdallah, Atiyeh; Abu madi, Marawan ( Qatar University Press , 2021 , Poster)
      Introduction: Bone density disorders are characterized by a reduction in bone mass density and strength, which lead to an increase in the susceptibility to sudden and unexpected fractures. Despite the serious consequences ...

    • Development and In Vivo Testing of Smart Nanoparticles for Enhanced Anti-Cancer Activity and Reduced Cardiotoxicity Associated with Tyrosine Kinase Inhibitors 

      Yalcin, Huseyin; Al-Thani, Hissa; Shurbaji, Samar ( Qatar University Press , 2021 , Poster)
      Tyrosine kinase inhibitors (TKIs) are new generation of anti-cancer drugs with very high efficiency against cancer cells. However, TKIs are associated with severe cardiotoxicity limiting their clinical benefits. One TKI ...

    • Comparison of Available Methods for Investigating The in vitro Activity of Colistin Against Different Gram-Negative Bacilli 

      Shams, Noora; AlHiraky, Hanin; Moulana, Nabila; Riahihi, Maissa; Alsowaidi, Kaltham; ... more authors ( Qatar University Press , 2021 , Poster)
      Background: The surge in the prevalence of multidrug-resistant (MDR) Gram-negative bacterial infections with limited treatment options and the decrease in the development of new antibiotics are challenges that lead to the ...

    • Is preexisting immunity to seasonal coronaviruses limited to cross-reactivity with SARS-CoV-2? A seroprevalence cross-sectional study in north-eastern France 

      Hadeel T., Zedan; Nasrallah, Gheyath K. ( Elsevier , 2021 , Article)
      In light of the ongoing coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), there remain unanswered questions regarding the humoral immune response and ...