Browsing Biomedical Sciences by Type "Master Thesis"
Now showing items 21-40 of 54
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The Expression of Retinal miRNA Evoked by Hyperglycemia and After Adiponectin Treatment in Human Retinal Endothelial Cells
(2018 , Master Thesis)Background: Diabetes mellitus is a chronic metabolic disease resulting in microvascular complications including diabetic retinopathy (DR). Adiponectin (ApN) is an adipokine hormone, and recent studies demonstrated that ApN ... -
GENERATION AND CHARACTERIZATION OF "OFF-THE-SHELF" CHIMERIC ANTIGEN RECEPTOR ENGINEERED T CELLS (CAR-T) TO TARGET CANCER PATIENTS WITH HEMATOLOGICAL MALIGNANCIES
(2021 , Master Thesis)Background: The usage of T cells engineered with a tumor-specific chimeric antigen receptor (CAR) for the therapeutic treatment of some types of hematological malignancies demonstrated great clinical success. However, the ... -
Genome-Wide Association Study (Gwas) To Uncover Genetic Risk Factors Associated With Low Bone Mineral Density And Osteoporosis In Qatar Population
(2019 , Master Thesis)Osteoporosis is an increasingly prevalent, global health burden characterized by low bone mineral density (BMD) and increased fracture risk. Despite the serious consequences of osteoporosis and the significant impact it ... -
IDENTIFICATION AND FUNCTIONAL VALIDATION OF RARE MISSENSE VARIANTS IN PLXNA1 AS A CANDIDATE GENE FOR SEVERE EARLY-ONSET OBESITY
(2024 , Master Thesis)Childhood obesity is a pressing issue in Qatar, with a reported prevalence of 49% among school-aged children and adolescents. This complex problem involves a combination of genetic and environmental factors. Monogenic ... -
The impact of COVID-19 crisis on the testing process of the Primary Health Care Corporation (PHCC) Laboratories in state of Qatar
(2023 , Master Thesis)Introduction The global healthcare systems have been significantly impacted by the coronavirus COVID-19 pandemic. It was a public health emergency that affects many health care services, including primary health care and ... -
IN-DEPTH CHARACTERIZATION OF MESENCHYMAL STEM CELLS-DERIVED EXTRACELLULAR VESICLES USING QUANTITATIVE PROTEOMICS
(2016 , Master Thesis)As they home in on injured tissue, modulate the immune system and support tissue repairing, mesenchymal stem cells (MSCs) are considered a promising tool for many therapeutic applications. In vitro, MSCs have been shown ... -
INTERACTION BETWEEN CLOCK GENE AND LIFESTYLE FACTOR IN RELATION TO OBESITY RISK FACTOR
(2024 , Master Thesis)Background: Circadian rhythms regulate vital biological processes affecting metabolic pathways. Its dysregulation is associated with obesity, cardiovascular diseases, insulin resistance, and other signs of metabolic syndrome. ... -
Investigating the Validity and Significance of Variant Calls by Next Generation Sequencing (NGS)
(2016 , Master Thesis)Whole genome or exome sequencing enables the fast generation of large volumes of data and is currently a hot topic in research. This technique has the subject of extensive research and has vast applications in healthcare ... -
INVESTIGATION OF THE HUMORAL IMMUNE RESPONSES IN SARS-COV-2 INFECTED AND VACCINATED INDIVIDUALS
(06-2 , Master Thesis)Background: Protective and lasting immunity to viral infections or vaccines are usually achieved through the combined actions of both cellular and humoral immune responses. Although there exists clear evidence supporting ... -
Latent Tuberculosis Infection Among Health Care Workers At The Communicable Disease Center In Qatar: Prevalence And Determinants
(2019 , Master Thesis)Background: To estimate the prevalence of latent Pulmonary Tuberculosis infection among healthcare workers in Communicable Disease Center (CDC) in Qatar and explore the factors associated with latent tuberculosis infection ... -
Machine Learning Prediction of Cancer from The Publicly Available Dataset
(2024 , Master Thesis)Prostate cancer in the second most common cause of cancer in men around the world and in Qatar with a high incidence rate worldwide. This has resulted in an increased mortality rate, making prostate cancer a healthcare ... -
Magnitude of RSV Fusion Protein-Specific Antibodies in Infants and Corresponding Mothers
(2018 , Master Thesis)INTRODUCTION: Respiratory syncytial virus (RSV) is a threatening agent causing lower respiratory infections (LRI) among children, where no vaccine is available. RSV expresses three surface glycoproteins, of which the ... -
Managing students with special educational needs; educator's perspective and training needs
(2023 , Master Thesis)Introduction: The number of students with special educational needs (SEN) who are able to attend higher education is increasing. Faculty members are the key players for the implementation of inclusion education and inclusion ... -
Molecular Analysis Of The Brca1 And Brca2 Genes In Hereditary Breast Or Ovarian Cancer Patients In Qatar (2015-2016)
(2018 , Master Thesis)The frequency of BRCA1 and BRCA2 mutations is understudied in Arab women and there are no studies investigating BRCA1/2 mutations in Qatar. In this study, we sequenced BRCA1 and BRCA2 genes in 183 patients suspected of ... -
NASAL EXPRESSION OF ANIOTENSIN-CONVERTING ENZYME 2 (ACE2) IN CHILDREN AND ADULTS WITH COVID-19
(2021 , Master Thesis)"Emerging evidence suggests that the lower expression of SARS-CoV-2 entry factor angiotensin-converting enzyme 2 (ACE2) and transmembrane serine protease 2 (TMPRSS2) in the nasal epithelium of children may contribute to ... -
National Study of Anaphylaxis in a Large Tertiary Care Hospital in Qatar: A Retrospective Study
(2018 , Master Thesis)Background: Anaphylaxis is a serious systemic allergic disease that often mani-fests with a broad array of symptoms and leads to death if not immediately treated by the administration of epinephrine auto-injector (EAI). ... -
Performance Evaluation for the HBVAND HCV Detection Protocols That Are Used By the Medical Commission Diagnostic Laboratory in Qatar
(2020 , Master Thesis)Background: Viral Hepatitis is regarded as a serious concern to human wellbeing, affecting millions of individuals yearly. The leading cause of this disease is the infection of Hepatitis A, B, C, D, and E. Consequently, ... -
Performance Evaluation for the HIV And Syphilis Detection Protocols Used By The Medical Commission Diagnostic Laboratory In Qatar
(2020 , Master Thesis)Background: The Medical Commission is responsible for screening all newcomers and expatriates in Doha, Qatar to ensure that infectious diseases do not enter the country. The infectious disease tests include; HIV, ... -
PROFILE OF LONG NON-CODING RNA IN RESPONSE TO SULFORAPHANE ANTI-OBESITY TREATMENT IN SKELETAL MUSCLES OF DIET INDUCED OBESITY MICE
(2023 , Master Thesis)Background: World Health Organization data reveal a rapid growth in obesity worldwide, making it a major public health concern. Obesity has been studied extensively in recent decades; however, it is still challenging due ... -
Profiling of Chronic Myeloid Neoplasms through RNA Sequencing Analysis
(2018 , Master Thesis)Background: Chronic myeloid leukemia (CML) is a clonal myeloproliferative disorder resulting from the neoplastic transformation of hematopoietic stem cells. A higher number of (54%) CML patients in Qatar failed to respond ...