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Humane care and use of laboratory animals training program (HCULA)
(2017 , Poster)
HCULA is the first basic training program that covers the use of Rodents as animals models in
biomedical research, it is composed of theory and hands on training courses . The theory
course is required to all students ...
Claudin-1, A Double-Edged Sword in Cancer.
(
MDPI
, 2020 , Article Review)
Claudins, a group of membrane proteins involved in the formation of tight junctions, are mainly found in endothelial or epithelial cells. These proteins have attracted much attention in recent years and have been implicated ...
Association of genes with phenotype in autism spectrum disorder.
(
Impact Journals
, 2019 , Article Review)
Autism spectrum disorder (ASD) is a genetic heterogeneous neurodevelopmental disorder that is characterized by impairments in social interaction and speech development and is accompanied by stereotypical behaviors such as ...
Cadmium-induced endothelial dysfunction mediated by asymmetric dimethylarginine.
(
Springer
, 2020 , Article)
Cadmium (Cd) is a naturally occurring toxic heavy metal with no known essential biological functions. Exposure to Cd increases the risk of cardiovascular disease by disrupting vascular homeostasis at the endothelium. The ...
Real-Time PCR Quantification of Metallothionein Gene Expression in Sprague–Dawley Rats Chronically Exposed to Cd
(
American Association for Laboratory Animal Science
, 2012 , Presentation)
Toxicologic impact of Cd leads to multiple human pathologic conditions,
and its effect on humans and animals has been extensively studied.
Physiologic function of metallothionein (MT1) is not completely understood,
but ...
NF-κB Essential MOdulator (NEMO) Is Critical for Thyroid Function
(
American Society for Biochemistry and Molecular Biology
, 2016 , Article)
The I-κB kinase (IKK) subunit NEMO/IKKγ (NEMO) is an adapter molecule that is critical for canonical activation of NF-κB, a pleiotropic transcription factor controlling immunity, differentiation, cell growth, tumorigenesis ...
Expression of active and inactive forms of CIK and CARMA 2sh proteins in Normal Human Epidermal Keratinocytes (NHEK)
(2016 , Poster)
Psoriasis is a debilitating skin disease affecting approximately 23% of human population. The disease is considered to have key genetic underpinning and genome wide association studies and meta analysis have identified ...
A Novel Mutation (Q694X) in the ITGB3 Gene Causing Glanzmann’s Thrombasthenia from the Sultanate of Oman
(
The American Society of Hematology
, 2008 , Article)
Background: Glanzmann Thrombasthenia (GT) results from mutations in the genes ITGA2B and ITGB3, located on chromosome 17q21–23 which encodes the platelet glycoprotein αIIbβ3 complex, namely GPIIb (αIIb) and GPIIIa (β3), ...
Animal Husbandry And Care
(2017 , Poster)
* Qatar University – Laboratory Animal Research Centre (LARC) is providing highest quality animal husbandry and care
* LARC is Specific pathogen Free (SPF) facility with state of the art animal housing & supporting ...
Extracellular vesicles-mediated intercellular communication: roles in the tumor microenvironment and anti-cancer drug resistance.
(
Springer Verlag
, 2019 , Article)
The tumor microenvironment represents a complex network, in which tumor cells not only communicate with each other but also with stromal and immune cells. Current research has demonstrated the vital role of the tumor ...