• 1H magnetic resonance spectroscopy of 2H-to-1H exchange quantifies the dynamics of cellular metabolism in vivo 

      Rich, Laurie J; Bagga, Puneet; Wilson, Neil E; Schnall, Mitchell D; Detre, John A; ... more authors ( Nature Research , 2020 , Article)
      Quantitative mapping of the in vivo dynamics of cellular metabolism via non-invasive imaging contributes to our understanding of the initiation and progression of diseases associated with dysregulated metabolic processes. ...
    • Animal Health Monitoring Program (AHMP) of LARC 

      Shanmugakonar, Muralitharan; Abujassoum, Hamda; Khan, Imran; Al Naemi, Hamda (2017 , Poster)
      Animal health monitoring is important to maintain the health of the animals used for research purpose. Maintaining healthy research animals is the prime requisite for best research outcomes. Health monitoring is performed ...
    • Animal Husbandry And Care 

      Govindharajan, Vijay Kanth; Kahsu, Tesfaldet; Sielu, Tesfom; Al Naemi, Hamda (2017 , Poster)
      * Qatar University – Laboratory Animal Research Centre (LARC) is providing highest quality animal husbandry and care * LARC is Specific pathogen Free (SPF) facility with state of the art animal housing & supporting ...
    • ANIMAL MODEL FOR CHILDHOOD OBESITY 

      Al-Naemi, Hamda; Das, Sandra Concepcion (2017 , Poster)
      Obesity has been recognized as a global health problem and linked with chronic diseases such as diabetes mellitus, cardiovascular syndromes, musculoskeletal disorders and some cancers. Children exposed to high carbohydrate, ...
    • Association of genes with phenotype in autism spectrum disorder. 

      Nisar, Sabah; Hashem, Sheema; Bhat, Ajaz A; Syed, Najeeb; Yadav, Santosh; ... more authors ( Impact Journals , 2019 , Article Review)
      Autism spectrum disorder (ASD) is a genetic heterogeneous neurodevelopmental disorder that is characterized by impairments in social interaction and speech development and is accompanied by stereotypical behaviors such as ...
    • Biosecurity And Biosafety In LARC 

      Govindharajan, Vijay Kanth; Tesfaldet, Kahsu; Tesfom, Sielu; Joseph, Benny; Al Naemi, Hamda (2017 , Poster)
      * LARC is Specific Pathogen Free(SPF) facility * LARC is free of Specific list of Pathogens maintained by routine testing. * Bio security & Bio safety are main components to maintain the LARC facility
    • Brain microstructural changes support cognitive deficits in HIV uninfected children born to HIV infected mothers 

      Santosh K., Yadav; Gupta, Rakesh K.; Hashem, Sheema; Nisar, Sabah; Azeem, Taha; ... more authors ( Elsevier , 2020 , Article)
      IntroductionAntiretroviral therapy (ART) is considered the most effective way to prevent perinatal transmission of human immunodeficiency virus (HIV). However, there is little knowledge about the effect of ART on the brain ...
    • Brain Microstructural Changes Support Cognitive Deficits in Normal Children Born to HIVinfected Mothers 

      Santosh Kumar Yadav, Rakesh K Gupta , Sabah N Ahmed , Sheema Hashem , Ajaz A Bhat , Ravindra K Garg , Vimala Venkatesh , Muhammad W Azeem , and Mohammad Haris.; Yadav, Santosh Kumar; Gupta, Rakesh K; Ahmed, Sabah N; Hashem, Sheema; ... more authors (2018 , Conference Proceedings)
      Synopsis In the current study, we evaluated the brain integrity [by mapping the fractional anisotropy (FA) and mean diffusivity (MD)] and neurocognitive performance (NP) in normal children (NCI) born to HIV-infected ...
    • Cadmium Toxicity: Oxidative Stress, Inflammation and Tissue Injury 

      Das, Sandra Concepcion; Al-Naemi, Hamda A. ( Scientific Research Publishing , 2019 , Article Review)
      Cadmium is a known environmental pollutant targeting various organs. Often implicated in cadmium toxicology is the formation of reactive oxygen species, overwhelming the free radical scavenging mechanisms and inducing ...
    • Cadmium-induced endothelial dysfunction mediated by asymmetric dimethylarginine. 

      Al-Naemi, Hamda A; Das, Sandra Concepcion ( Springer , 2020 , Article)
      Cadmium (Cd) is a naturally occurring toxic heavy metal with no known essential biological functions. Exposure to Cd increases the risk of cardiovascular disease by disrupting vascular homeostasis at the endothelium. The ...
    • Cadmium: An Emerging Role in Adipose Tissue Dysfunction 

      Attia, Sarra Mohammed; Varadharajan, Kavitha; Shanmugakonar, Muralitharan; Das, Sandra Concepcion; Al-Naemi, Hamda A. ( Springer , 2021 , Article Review)
      Cadmium (Cd) is a toxic heavy metal that is widespread in the environment due to the substantial anthropogenic inputs from the agriculture and industrial sectors. The toxic impact of Cd adversely affects human health and ...
    • Cardiac Myosin Binding Protein-C in Sprague Dawley (SD) Rats exposed to Sub-Chronic oral dose of Cadmium Chloride 

      Al-Borshaid, Enjoud Khalifa; Varadharajan, Kavitha; Shanmugakonar, Muralitharan; Al-Naemi, Hamda ( Qatar University Press , 2021 , Poster)
      Cadmium is one of the major environmental pollutants associated with an increment in industrial and urbanization activities. It has health consequences when it reaches the human diet through the soil, water, and plant. ...
    • CARMA2sh and ULK2 control pathogen-associated molecular patterns recognition in human keratinocytes: psoriasis-linked CARMA2sh mutants escape ULK2 censorship 

      Scudiero, Ivan; Mazzone, Pellegrino; D'Andrea, Luca E.; Ferravante, Angela; Zotti, Tiziana; ... more authors ( Nature , 2017 , Article)
      The molecular complexes formed by specific members of the family of CARMA proteins, the CARD domain-containing adapter molecule BCL10 and MALT1 (CBM complex) represent a central hub in regulating activation of the pleiotropic ...
    • Changes in resting-state functional brain activity are associated with waning cognitive functions in HIV-infected children. 

      Yadav, Santosh K; Gupta, Rakesh K; Hashem, Sheema; Bhat, Ajaz A; Garg, Ravindra K; ... more authors ( Elsevier , 2018 , Article)
      Delayed brain development in perinatally HIV-infected children may affect the functional brain activity and subsequently cognitive function. The current study evaluated the functional brain activity in HIV-infected children ...
    • Chemokine-cytokine networks in the head and neck tumor microenvironment 

      Nisar, Sabah; Yousuf, Parvaiz; Masoodi, Tariq; Wani, Nissar A.; Hashem, Sheema; ... more authors ( MDPI , 2021 , Article Review)
      Head and neck squamous cell carcinomas (HNSCCs) are aggressive diseases with a dismal patient prognosis. Despite significant advances in treatment modalities, the five-year survival rate in patients with HNSCC has improved ...
    • Chronic Cadmium Exposure Alters Cardiac Matrix Metalloproteinases in the Heart of Sprague-Dawley Rat 

      Das, Sandra Concepcion; Varadharajan, Kavitha; Shanmugakonar, Muralitharan; Al-Naemi, Hamda A. ( Frontiers Media , 2021 , Article)
      The aim of this study was to evaluate the role of chronic cadmium exposure in modulating cardiac matrix metalloproteinases (MMPs) in the heart of rats. Adult male Sprague-Dawley rats were exposed to 15 ppm CdCl2 in drinking ...
    • Claudin-1, A Double-Edged Sword in Cancer. 

      Bhat, Ajaz A; Syed, Najeeb; Therachiyil, Lubna; Nisar, Sabah; Hashem, Sheema; ... more authors ( MDPI , 2020 , Article Review)
      Claudins, a group of membrane proteins involved in the formation of tight junctions, are mainly found in endothelial or epithelial cells. These proteins have attracted much attention in recent years and have been implicated ...
    • Cytokine-chemokine network driven metastasis in esophageal cancer; promising avenue for targeted therapy 

      Bhat, A.A.; Bhat, Ajaz A.; Nisar, Sabah; Maacha, Selma; Carneiro-Lobo, Tatiana Correa; ... more authors ( BMC , 2021 , Article Review)
      Esophageal cancer (EC) is a disease often marked by aggressive growth and poor prognosis. Lack of targeted therapies, resistance to chemoradiation therapy, and distant metastases among patients with advanced disease account ...
    • Diagnostic Microbiology Laboratory Monitoring of LARC 

      Khan, Imran; Shanmugakonar, Muralitharan; Aboujassoum, Hamda; Al Naemi, Hamda (2017 , Poster)
      Microbial free environment of a research facility is critical to maintain animal health. Establishing Microbiological Monitoring Program is mandatory to assure the quality of the system. Microbiological monitoring involves ...
    • Effect of CARMA 2sh gene in Mouse embryonic stem (ES) cells 

      Shanmugakonar, Muralitharan; Varadharajan, Kavitha; Vito, Pasquale (2017 , Poster)
      CARMA2 belongs to the CARMA family of proteins. They are involved in the regulation and activation of NF-κB that have a central role in the control of immune and inflammatory response, and cell survival and proliferation. ...