HER-2/Epstein-Barr virus crosstalk in human gastric carcinogenesis: A novel concept of oncogene/oncovirus interaction.
| المؤلف | Cyprian, Farhan S |
| المؤلف | Al-Antary, Noor |
| المؤلف | Al Moustafa, Ala-Eddin |
| تاريخ الإتاحة | 2019-10-16T06:55:13Z |
| تاريخ النشر | 2018-01-02 |
| اسم المنشور | Cell Adhesion and Migration |
| المعرّف | http://dx.doi.org/10.1080/19336918.2017.1330244 |
| الاقتباس | Ruizhen Liu, Yi Kong, Pengbo Sun, Faliang Li, Xiaopeng Shi. (2019) Correlation between methylation of the caveolin‐1 gene and of caveolin‐1 messenger ribonucleic acid, and protein levels and human epidermal growth factor receptor 2 protein expression in adenocarcinomas of the esophagogastric junction. Precision Radiation Oncology 3:1, pages 8-14. |
| الرقم المعياري الدولي للكتاب | 1933-6918 |
| الملخص | Gastric cancer is the fourth most common cancer and the second leading cause of cancer deaths worldwide. Additionally, it is well-known that metastatic cancer disease is a major cause of morbidity and mortality in cancer patients. Several investigations reported that HER-2 (ErbB-2 receptor) and Epstein-Barr virus (EBV) are important etiological factors in human gastric cancer, where either oncogene/oncovirus alone can derive a major event of cancer progression and metastasis via epithelial-mesenchymal transition (EMT). Herein, we discuss, for the first time, the possibility of HER-2/EBV-oncoproteins interaction in human gastric cancer initiation and/or progression. |
| راعي المشروع | Our research is supported by the College of Medicine and Qatar University. |
| اللغة | en |
| الناشر | Taylor & Francis |
| الموضوع | EBV HER-2 cancer initiation and progression gastric cancer oncogene/oncovirus cooperation |
| النوع | Article |
| الصفحات | 1-4 |
| رقم العدد | 1 |
| رقم المجلد | 12 |
| ESSN | 1933-6926 |
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