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E-cadherin/catenin complex modulations in human oral cancer
( Springer Netherlands , 2015 , Book chapter)Oral cancer is a common neoplasm in both male and female worldwide; the incidence and mortality of this cancer have increased over the past decades. Cancer metastasis is a major cause of morbidity and mortality in oral ... -
An interdisciplinary specialist team leads to improved diagnostics and treatment for paediatric patients with vascular anomalies
( John Wiley & Sons Ltd. , 2015 , Article)Aim Patients with vascular anomalies are often misdiagnosed, leading to delayed or improper treatment. The aim of this study was to evaluate the impact of an interdisciplinary team on the diagnosis and treatment of ... -
The Role of CCL21/CCR7 Chemokine Axis in Breast Cancer Progression
( MDPI , 2015 , Article Review)Tumor-induced lymphangiogenesis facilitates breast cancer progression by generating new lymphatic vessels that serve as conduits for tumor dissemination to lymph nodes and beyond. Given the recent evidence suggesting the ... -
E5 and E6/E7 of high-risk HPVs cooperate to enhance cancer progression through EMT initiation
( Taylor & Francis , 2015 , Article)It is estimated that 10–20% of human carcinogenesis is linked to virus infection including papillomaviruses (HPVs). Moreover, since metastatic cancer disease is a major cause of morbidity and mortality in cancer patients, ... -
Breast carcinoma metastasis suppressor gene 1 (BRMS1): update on its role as the suppressor of cancer metastases.
( Springer , 2015 , Article)BRMS1 was discovered over a decade ago as a potential tumor suppressor gene. In this review, we summarize the recent findings about the structure of BRMS1, mechanisms of its action and a role of BRMS1 in the cancer ... -
A Qualitative Study on Implementation of the Intelligent Bed: Findings from a Rehabilitation Ward at a Large Chinese Tertiary Hospital
( Springer New York LLC , 2016 , Article)The intelligent bed, a mechanical hospital bed equipped with several electronic sensor functions, is an assistive healthcare solution intended to reduce the manual workload of health professionals by providing valuable ... -
Solely abluminal drug release from coronary stents could possibly improve reendothelialization
( John Wiley and Sons Inc. , 2016 , Article)Objectives To compare a new stent with an asymmetric coating, eluting the drug to the abluminal surface, to a stent with a conventional coating eluting the drug both to the luminal and the abluminal side. Background Stents ... -
Association of β-Adrenergic Receptor Gene Polymorphisms With Acute Coronary Syndrome and Cardiovascular Risk Factors in an Arab Population
( SAGE Publications Inc. , 2016 , Article)We evaluated the association between beta-adrenergic receptor genes (ADRB1 and ADRB2) polymorphism, cardiovascular risk, and acute coronary syndrome (ACS) in individuals from an Arab ethnicity. A total of 388 Qatari ... -
Progress and challenges in the proteomics of domestic pig in research on the female reproductive system
( Polish Society Magnesium Research , 2016 , Article)The proteomics of pigs is developing dynamically, attracting much attention among representatives of medical and health sciences, veterinary medicine, agricultural and natural sciences. The pig has been widely studied in ... -
Prevalence of fibularis tertius muscle in South-eastren Indian populat1ion: A surface anatomical study
( TIP ARASTIRMALARI DERNEGI , 2016 , Article)Background: Fibularis tertius (FT) is a variant muscle of the anterior compartment of leg which involves in dorsiflexion and evertion of the foot. Literature shows that the reported prevalence of FT ranges from 49-100%. ... -
Generalisability theory analyses of concept mapping assessment scores in a problem-based medical curriculum
( Blackwell Publishing Ltd , 2016 , Article)Context In problem-based learning (PBL), students construct concept maps that integrate different concepts related to the PBL case and are guided by the learning needs generated in small-group tutorials. Although an ... -
Metronidazole in conjunction with penicillin neither prevents recurrence nor enhances recovery from peritonsillar abscess when compared with penicillin alone: A prospective, double-blind, randomized, placebo-controlled trial
( Oxford University Press , 2016 , Article)Objectives The objectives of this study were to evaluate the efficacy of metronidazole in conjunction with penicillin in preventing the recurrence of peritonsillar abscess (PTA) and to learn whether metronidazole enhances ... -
Effects of topiramate on pregnancy outcome in rats
( Bahrain Medical Bulletin , 2016 , Article)Background: Anti-epileptics taken during pregnancy might lead to low birth-weight and birth defects which could be associated with neonatal morbidity and mortality. Objective: To evaluate the effects of maternal exposure ... -
Personalized telehealth in the future: A global research agenda
( JMIR Publications Inc. , 2016 , Article Review)As telehealth plays an even greater role in global health care delivery, it will be increasingly important to develop a strong evidence base of successful, innovative telehealth solutions that can lead to scalable and ... -
Mutations in PLCδ1 associated with hereditary leukonychia display divergent PIP2 hydrolytic function
( Blackwell Publishing Ltd , 2016 , Article)Hereditary leukonychia is a rare genetic nail disorder characterized by distinctive whitening of the nail plate of all 20 nails. Hereditary leukonychia may exist as an isolated feature, or in simultaneous occurrence with ... -
Targeted delivery of rifampicin to tuberculosis-infected macrophages: design, in-vitro, and in-vivo performance of rifampicin-loaded poly(ester amide)s nanocarriers
( Elsevier B.V. , 2016 , Article)We have developed a nano drug delivery system for the treatment of tuberculosis (TB) using rifampicin (RF) encapsulated in poly(ester amide)s nanoparticles (PEA-RF-NPs), which are biocompatible polymers. In this study, ... -
Prevalence of fibularis tertius muscle in South-eastren Indian populat1ion: A surface anatomical study
( TIP ARASTIRMALARI DERNEGI , 2016 , Article)Background: Fibularis tertius (FT) is a variant muscle of the anterior compartment of leg which involves in dorsiflexion and evertion of the foot. Literature shows that the reported prevalence of FT ranges from 49-100%. ... -
Lecturing skills as predictors of tutoring skills in a problem-based medical curriculum
( Dove Press , 2016 , Article)Purpose: Recruitment of tutors to work in problem-based learning (PBL) programs is challenging, especially in that most of them are graduated from discipline-based programs. Therefore, this study aims at examining whether ... -
Oligomeric and phosphorylated alpha-synuclein as potential CSF biomarkers for Parkinson’s disease
( BioMed Central , 2016 , Article)Background Despite decades of intensive research, to date, there is no accepted diagnosis for Parkinson’s disease (PD) based on biochemical analysis of blood or CSF. However, neurodegeneration in the brains of PD patients ... -
Impact of single-walled carbon nanotubes on the embryo: a brief review
( Dove Press , 2016 , Article)Carbon nanotubes (CNTs) are considered one of the most interesting materials in the 21st century due to their unique physiochemical characteristics and applicability to various industrial products and medical applications. ...
