Medicine Research: المرسلات الحديثة
السجلات المعروضة 401 -- 420 من 1485
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Analysis of the Origin of Emiratis as Inferred from a Family Study Based on HLA-A, -C, -B, -DRB1, and -DQB1 Genes
( MDPI , 2023 , Article)In this study, we investigated HLA class I and class II allele and haplotype frequencies in Emiratis and compared them to those of Asian, Mediterranean, and Sub-Saharan African populations. Methods: Two-hundred unrelated ... -
Stress Factors as Possible Regulators of Pluripotent Stem Cell Survival and Differentiation
( MDPI , 2023 , Article Review)In recent years, extensive research efforts have been directed toward pluripotent stem cells, primarily due to their remarkable capacity for pluripotency. This unique attribute empowers these cells to undergo self-renewal ... -
Antibiotics Prescriptions Pattern among Patients Visiting Primary Health Care Centers (PHCC) before and during COVID-19 Pandemic: A Cross-Sectional Population-Based Study from Qatar
( MDPI , 2023 , Article)Background: The COVID-19 pandemic, caused by the novel coronavirus 2 (SARS-CoV-2), has been associated with an increased risk of secondary bacterial infections. Numerous studies have reported a surge in antibiotic usage ... -
Assay-agnostic spatial profiling detects tumor microenvironment signatures: new diagnostic insights for triple-negative breast cancer
( John Wiley and Sons Ltd , 2023 , Article)The role of the tumor microenvironment (TME) in immuno-oncology has driven demand for technologies that deliver in situ, or spatial, molecular information. Compartmentalized heterogeneity that traditional methods miss is ... -
World Marrow Donor Association guidelines for the reporting of novel HLA alleles
( John Wiley and Sons Inc , 2023 , Article)The guidelines for the implementation and reporting of HLA nomenclature for the World Marrow Donor Association have served as a reliable standard for communication of HLA data in the hematopoietic cell transplantation ... -
KIR genotype and haplotype repertoire in Kuwaiti healthy donors, hematopoietic cell transplant recipients and healthy family members
( John Wiley and Sons Inc , 2023 , Article)The gene complex located on chromosome 19q13.4 encodes the Killer-cell Immunoglobulin-like Receptors (KIRs), which exhibit remarkable polymorphism in both gene content and sequences. Further, the repertoire of KIR genes ... -
Preliminary investigation of elevated collagen and blood-clotting markers as potential noninvasive biomarkers for small cell lung cancer
( John Wiley and Sons Inc , 2023 , Article)Background: Small cell lung cancer (SCLC) is highly aggressive with limited therapeutic options and a poor prognosis. Moreover, noninvasive biomarker tools for detecting disease and monitoring treatment response are lacking. ... -
‘Q-Storming’ to identify challenges and opportunities for integrating health and climate adaptation measures in Africa
( Elsevier , 2023 , Article)Introduction: Climate factors influence the state of human health and wellbeing. Climate-related threats are particularly being experienced by vulnerable populations in Africa. A Question (Q)-Storming session was convened ... -
Monoacylglycerol lipase reprograms hepatocytes and macrophages to promote liver regeneration
( Elsevier , 2023 , Article)Background & Aims: Liver regeneration is a repair process in which metabolic reprogramming of parenchymal and inflammatory cells plays a major role. Monoacylglycerol lipase (MAGL) is an ubiquitous enzyme at the crossroad ... -
Helicobacter pylori and epithelial mesenchymal transition in human gastric cancers: An update of the literature
( Elsevier , 2023 , Article Review)Gastric cancer, a multifactorial disease, is considered one of the most common malignancies worldwide. In addition to genetic and environmental risk factors, infectious agents, such as Epstein-Barr virus (EBV) and Helicobacter ... -
IP3 receptors: An "elementary" journey from structure to signals
( Elsevier , 2023 , Article)Inositol 1,4,5-trisphosphate receptors (IP3Rs) are large tetrameric channels which sit mostly in the membrane of the endoplasmic reticulum (ER) and mediate Ca2+ release from intracellular stores in response to extracellular ... -
Spontaneous closure of the large idiopathic full-thickness macular hole
( Elsevier , 2023 , Other)Dear Editor, Idiopathic full-thickness macular hole (FTMH) represents an interruption in all retina layers from the internal limiting membrane to the photoreceptors, is unrelated to any other ocular or systemic conditions, ... -
Late-diagnosed complete intravaginal testicular torsion with preserved blood flow and viable testis in an adolescent
( Elsevier , 2023 , Article)To the Editor, Testicular torsion (TT) is an emergency caused by the twisting of the spermatic cord. In addition to being complete, TT can be partial or intermittent. The degree of spermatic cord twist in partial or ... -
Correction to: A qualitative assessment of medical students' readiness for virtual clerkships at a Qatari university during the COVID-19 pandemic (BMC Medical Education, (2023), 23, 1, (186), 10.1186/s12909-023-04117-3)
( BioMed Central Ltd , 2023 , Other)Correction: BMC Medical Education (2023) 23:186 Following publication of the original article [1], due to a typesetting error, references [19] and [20] were written incorrectly. The correct references are given below: [19] ... -
Advanced adult granulosa cell tumor with prominent fibromatous stroma: A case report
( Elsevier , 2023 , Article)To the Editor, Adult granulosa cell tumor (AGCT) is the most common sex cord–stromal tumor and accounts for about 1% of all ovarian neoplasms.1 It is derived from granulosa cells of the ovarian follicle that are responsible ... -
Perinatal factors impacting echocardiographic left ventricular measurement in small for gestational age infants: a prospective cohort study
( BioMed Central Ltd , 2023 , Article)Introduction: Infants born small for gestational age (SGA) have an increased risk of developing various cardiovascular complications. While many influencing factors can be adjusted or adapt over time, congenital factors ... -
Barriers and facilitators of older adults for professional mental health help-seeking: a systematic review
( BioMed Central Ltd , 2023 , Article)Background: Older adults are at an increased risk for mental health issues, yet they are less likely to seek professional help. This systematic review aims to identify and summarize literature on the barriers and facilitators ... -
Mental illness stigma as a moderator in the relationship between religiosity and help-seeking attitudes among Muslims from 16 Arab countries
( BioMed Central Ltd , 2023 , Article)Background Determining the potential barriers responsible for delaying access to care, and elucidating pathways to early intervention should be a priority, especially in Arab countries where mental health resources are ... -
Unveiling a Biomarker Signature of Meningioma: The Need for a Panel of Genomic, Epigenetic, Proteomic, and RNA Biomarkers to Advance Diagnosis and Prognosis
( MDPI , 2023 , Article Review)Meningiomas are the most prevalent primary intracranial tumors. The majority are benign but can undergo dedifferentiation into advanced grades classified by World Health Organization (WHO) into Grades 1 to 3. Meningiomas’ ... -
Exploring the Role of microRNAs in Glioma Progression, Prognosis, and Therapeutic Strategies
( MDPI , 2023 , Article)Gliomas, which arise from glial cells in the brain, remain a significant challenge due to their location and resistance to traditional treatments. Despite research efforts and advancements in healthcare, the incidence of ...
