Medicine Research: المرسلات الحديثة
السجلات المعروضة 1 -- 20 من 2057
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Hormonal Modulation of Fat Mass Induced Insulin Resistance
( Mary Ann Liebert Inc. , 2025 , Article)Objective: This study examines the impact of body mass index (BMI) on homeostatic model assessment for insulin sensitivity (HOMA-S) and homeostatic model assessment for pancreatic β-cell function (HOMA-B) in adults with ... -
Gestational Diabetes Is Associated With Abnormalities in Glucose Excursion in Early Pregnancy
( John Wiley and Sons Ltd , 2025 , Article)Aims: It is unknown if dysglycemia at 24–28 weeks of pregnancy is preceded by glycemic changes earlier in pregnancy. This study therefore examines the association between glucose excursion in the first 20 gestational weeks ... -
Comparative survival outcomes between therapy-related and de novo acute lymphoblastic leukemia in adults: a systematic review and meta-analysis
( BioMed Central Ltd , 2025 , Article)Background: Therapy-related acute lymphoblastic leukemia (t-ALL) is an aggressive subtype of ALL that arises after cytotoxic therapy. It is associated with adverse cytogenetics and older age, but survival outcomes compared ... -
Examining and Interpreting Doi Plot Asymmetry in Meta-Analyses of Randomized Controlled Trials
( John Wiley and Sons Inc. , 2025 , Article)Systematic reviews and meta-analyses are considered the highest level of evidence, but their reliability can be undermined by publication bias. Traditional methods for assessing publication bias, such as funnel plots and ... -
Association Between Pre-Existing Conditions and COVID-19 Hospitalization, Intensive Care Services, and Mortality: A Cross-Sectional Analysis of an International Global Health Data Repository
( Multidisciplinary Digital Publishing Institute (MDPI) , 2025 , Article)Background: The use of globally shared individual-level data in answering epidemiological questions during health emergencies of international concern is still debatable. In this study, we investigated the association ... -
Global disparities in adrenaline access: A World Allergy Organization call for equity in anaphylaxis care
( Elsevier , 2025 , Article)Anaphylaxis is a medical emergency and can be fatal if not treated immediately.1,2 Adrenaline remains the only effective first-line treatment capable of reversing anaphylaxis in all settings, including in the community,1,2 ... -
Hybrid Neural Networks for Precise Hydronephrosis Classification Using Deep Learning
( Elsevier , 2025 , Article)ObjectiveTo develop and evaluate a deep learning framework for automatic kidney and fluid segmentation in renal ultrasound images, aiming to enhance diagnostic accuracy and reduce variability in hydronephrosis assessment. ... -
Low-Intensity Ultrasound and Neural Repair: Unlocking Brain Plasticity and Functional Recovery
( Elsevier , 2026 , Article Review)Emerging evidence highlights the potential of transcranial focused ultrasound in enhancing brain function and repair. Low-intensity focused ultrasound (LIFUS) enables precise, non-invasive modulation of neuronal activity, ... -
Dual COX/5-LOX inhibition by isorhamnetin-3-O-glucoside from Anthyllis cytisoides: An integrated chemical-enzymatic-computational study
( Elsevier , 2026 , Article)Ethnopharmacological relevanceAnthyllis cytisoides L. is a forage shrub native to the western Mediterranean basin, traditionally used in folk medicine to treat respiratory and gastrointestinal inflammation. However, its ... -
The role of small, dense lipoproteins in type-2 diabetes and maturity-onset diabetes of the young (MODY): What's new
( Elsevier , 2025 , Article)Although diabetic dyslipidemia is a well-known and extensively studied phenomenon, its features continue to attract significant attention from both researchers and clinicians. Given that lipid profile abnormalities are ... -
Liposomal delivery of DK14 chalcone analogue: A promising therapeutic strategy against triple-negative breast cancer
( Elsevier , 2026 , Article)Triple negative breast cancer (TNBC) is considered the most aggressive type of breast malignancy. TNBC management approaches remain limited, with a high risk of relapse and metastasis. Chalcone compounds are established ... -
A novel virtual patient approach for cross-patient multimodal fusion in enhanced breast cancer detection
( Elsevier , 2026 , Article)Multimodal medical imaging combining conventional imaging modalities such as mammography, ultrasound, and histopathology has shown significant promise for improving breast cancer detection accuracy. However, clinical ... -
Correction: Carnosol Induces ROS-Mediated Beclin1-Independent Autophagy and Apoptosis in Triple Negative Breast Cancer (PLoS One (2014) 9:10 (e109630) DOI: 10.1371/journal.pone.0109630)
( Public Library of Science (PLOS) , 2025 , Article)There are errors in Figs 3 and 8. Specifically, • In Fig 3A, the Early Apop. values reported in the lower right quadrants of the Control, 50 µM, and 100 µM panels are incorrect. A corrected Fig 3 is provided with this ... -
The Promise of Exosomes in Cardiac Repair: When ‘Best Things Come in Small Packages’
( John Wiley and Sons Inc , 2025 , Article)Myocardial ischaemia continues to be a predominant global cause of mortality, leaving survivors with compromised quality of life and significant loss of functional cardiomyocytes. The main therapeutic approach, which ... -
Rare presentation of lues maligna and nodular syphilis in an immunocompetent patient
( Elsevier , 2026 , Report)Secondary syphilis can present in many ways; common presentations of secondary syphilis include a generalized papulosquamous or pitriasifrom generalized eruption that commonly affects the palms and soles.1 Recently, a rapid ... -
7-O-methylpunctatin is a potential inhibitor of human arachidonate 5-lipoxygenase: molecular and structural insights into anti-atherosclerosis therapeutics
( Springer Nature , 2026 , Article)We have recently demonstrated that 7-O-methylpunctatin (MP), a novel homoisoflavonoid, suppresses inflammation-induced arterial pathogenesis. However, the precise biochemical mechanisms underlying its atheroprotective ... -
Reduced appetite after body contouring is associated with low glucose-dependent insulinotropic polypeptide levels
( Elsevier , 2025 , Article)Gut hormone modulation is central to appetite regulation following bariatric surgery, but its relevance among individuals undergoing body contouring procedures, with or without bariatric surgery, remains unclear. In this ... -
Severe Blepharokeratoconjunctivitis in Children—The Toronto Experience
( Elsevier , 2026 , Article)PurposeTo report on the clinical characteristics and treatment outcomes of a large cohort of pediatric patients who presented with severe blepharokeratoconjunctivitis (BKC). DesignRetrospective consecutive cohort study. ... -
Global age-sex-specific all-cause mortality and life expectancy estimates for 204 countries and territories and 660 subnational locations, 1950–2023: a demographic analysis for the Global Burden of Disease Study 2023
( Elsevier , 2025 , Article)Comprehensive, comparable, and timely estimates of demographic metrics—including life expectancy and age-specific mortality—are essential for evaluating, understanding, and addressing trends in population health. The ... -
Zebrafish: A Versatile and Powerful Model for Biomedical Research
( John Wiley and Sons Inc , 2025 , Article)Zebrafish (Danio rerio) have become a versatile model in precision medicine, bridging fundamental biology with translational applications. Their optical transparency, rapid development, and high genetic conservation with ...
