Medicine Research: Recent submissions
Now showing items 621-640 of 1508
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Prevalence of Venous Thromboembolism in Critically Ill COVID-19 Patients: Systematic Review and Meta-Analysis
( Frontiers Media S.A. , 2021 , Article)Background: Recent studies revealed a high prevalence of venous thromboembolism (VTE) events in coronavirus disease 2019 (COVID-19) patients, especially in those who are critically ill. Available studies report varying ... -
Cerebrospinal fluid α-synuclein species in cognitive and movements disorders
( Multidisciplinary Digital Publishing Institute (MDPI) , 2021 , Article)Total CSF α-synuclein (t-α-syn), phosphorylated α-syn (pS129-α-syn) and α-syn oligomers (o-α-syn) have been studied as candidate biomarkers for synucleinopathies, with suboptimal specificity and sensitivity in the ... -
Non-ST-Segment Elevation Myocardial Infarction Shortly After Starting Steroid Replacement Therapy in a Patient With Adrenal Insufficiency.
(2022 , Article)Adrenal insufficiency is a rare disorder that results from etiological factors affecting either the hypothalamic-pituitary axis or the adrenal gland itself. Studies have associated an inherently increased risk of cardiovascular ... -
Carnosol Induces p38-Mediated ER Stress Response and Autophagy in Human Breast Cancer Cells
( Frontiers , 2022 , Article)We recently reported that carnosol induces ROS-dependent autophagy and apoptosis in breast cancer cells. We also reported that carnosol inhibits breast cancer cell migration, invasion, and in ovo tumor growth, as well as ... -
The Impact of Sleeve Gastrectomy on Gastroesophageal Reflux Disease in Patients with Morbid Obesity: a letter to the editor
( springer link , 2022 , Article)Sancho et al.’s recent report on the effect of laparoscopic sleeve gastrectomy (LSG) on the symptomatology of gastroesophageal reflux disease (GERD) was both interesting and timely [1]. Their finding of a significant ... -
Cardioprotective Effect of Rheum turkestanicum Against Doxorubicin-Induced Toxicity in Rats
( Frontiers Media S.A. , 2022 , Article)Background: Doxorubicin as an anti-cancer drug causes cardiotoxicity, limiting its tolerability and use. The mechanism of toxicity is due to free radical production and cardiomyocytes injury. This research evaluated Rheum ... -
Cardiac Arrest in an Adolescent Boy Due to the Anomalous Origin of the Left Main Coronary Artery: Emergency Department Perspective.
( Cureus , 2022 , Article)Congenital anomalies of the origin of the coronary arteries are rare. Multiple anomalies have been reported where the common one is left circumflex arising from the right sinus of Valsalva (RSV). Other anomalies are a ... -
Outcomes of guideline-based medical therapy in patients with acute heart failure and reduced left ventricular ejection fraction: Observations from the Gulf acute heart failure registry (Gulf CARE)
( Medicine (Baltimore) , 2022 , Article)AbstractThis study aimed to report on the use, predictors and outcomes of guideline-based medical therapy (GBMT) in patients with acute heart failure (HF) with reduced ejection fraction of <40% (HFrEF), from seven countries ... -
Carbimazole-Induced Jaundice in Thyrotoxicosis: A Case Report.
( Springer , 2021 , Article)Carbimazole is a commonly used antithyroid drug in thyrotoxicosis. It is generally well tolerated, and its side effects include allergic skin reactions, gastrointestinal upset, agranulocytosis, and hepatotoxicity. Hepatitis ... -
Haemoglobin cut-off values for the diagnosis of anaemia in preschool-age children.
( e-Century Publishing , 2021 , Article)The World Health Organisation (WHO) suggests haemoglobin that (Hgb) cut-off levels below 2SD from the population mean to initiate anaemia investigations. In the absence of epidemiological data, Hgb less than 11 g/dL is ... -
Vasoactive pharmacologic therapy in cardiogenic shock: a critical review.
( Taylor & Francis , 2021 , Article)Cardiogenic shock (CS) is an acute complex condition leading to morbidity and mortality. Vasoactive medications, such as vasopressors and inotropes are considered the cornerstone of pharmacological treatment of CS to improve ... -
Proatherogenic sialidases and desialylated lipoproteins: 35 years of research and current state from bench to bedside
( Multidisciplinary Digital Publishing Institute (MDPI) , 2021 , Article)This review summarizes the main achievements in basic and clinical research of atheroscle-rosis. Focusing on desialylation as the first and the most important reaction of proatherogenic pathological cascade, we speak of ... -
A response to “doctors' challenges during infectious disease outbreaks: Medical education insights from realistic fiction movies” [response to letter]
( Dove Medical Press , 2021 , Article)First, I would like to thank Choi et al (2021)6 for their thorough reading and valuable comments on my published paper “Doctors’ Challenges During Infectious Disease Outbreaks: Medical Education Insights from Realistic ... -
COVID-19 in a pregnant patient with beta-thalassemia major: A case report
( Wiley-Blackwell , 2021 , Article)Further studies are needed on this unique population to better manage them and increase their chances of normal pregnancy and fewer complications and more favorable outcomes. -
Heterotopic pregnancy after a spontaneous conception a case report with a review of clinical, laboratory and imaging findings.
( Wiley , 2021 , Article)Heterotopic pregnancy (HP) describes the simultaneous presence of two pregnancies at different implantation sites. Usually, one pregnancy is intrauterine and the other one is ectopic. The incidence of HP after assisted ... -
Perirenal Adipose Tissue Inflammation: Novel Insights Linking Metabolic Dysfunction to Renal Diseases
( Frontiers Media S.A. , 2021 , Article)A healthy adipose tissue (AT) is indispensable to human wellbeing. Among other roles, it contributes to energy homeostasis and provides insulation for internal organs. Adipocytes were previously thought to be a passive ... -
Clinical significance of P-class pumps in cancer (Review)
( Spandidos Publications , 2021 , Article)P-class pumps are specific ion transporters involved in maintaining intracellular/extracellular ion homeostasis, gene transcription, and cell proliferation and migration in all eukaryotic cells. The present review aimed ... -
Hyperosmotic Stress Induces a Specific Pattern for Stress Granule Formation in Human-Induced Pluripotent Stem Cells
( Hindawi , 2021 , Article)Stress granules (SGs) are assemblies of selective messenger RNAs (mRNAs), translation factors, and RNA-binding proteins in small untranslated messenger ribonucleoprotein (mRNP) complexes in the cytoplasm. Evidence indicates ... -
Studies of Glyoxalase 1-Linked Multidrug Resistance Reveal Glycolysis-Derived Reactive Metabolite, Methylglyoxal, Is a Common Contributor in Cancer Chemotherapy Targeting the Spliceosome
( Frontiers Media S.A. , 2021 , Article)Background: Tumor glycolysis is a target for cancer chemotherapy. Methylglyoxal (MG) is a reactive metabolite formed mainly as a by-product in anaerobic glycolysis, metabolized by glyoxalase 1 (Glo1) of the glyoxalase ... -
Beta-caryophyllene exhibits anti-proliferative effects through apoptosis induction and cell cycle modulation in multiple myeloma cells
( Multidisciplinary Digital Publishing Institute (MDPI) , 2021 , Article)Cannabinoid receptors, which are widely distributed in the body, have been considered as possible pharmacological targets for the management of several tumors. Cannabinoid type 2 receptors (CB2Rs) belong to the G protein-coupled ...
