Medicine Research: Recent submissions
Now showing items 521-540 of 1485
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Association of Blood Levels of Vitamin D and Its Binding Protein with Clinical Phenotypes of Multiple Sclerosis.
( MDPI , 2023 , Article)Low vitamin D levels may synergize with changing levels of the vitamin D binding protein (DBP) to precipitate in the development and clinical progression of multiple sclerosis (MS). In this study, this hypothesis was ... -
Data extraction error in pharmaceutical versus non-pharmaceutical interventions for evidence synthesis: Study protocol for a crossover trial
( Elsevier , 2023 , Article)BackgroundData extraction is the foundation for research synthesis evidence, while data extraction errors frequently occur in the literature. An interesting phenomenon was observed that data extraction error tend to be ... -
Adverse childhood experiences, the risk of pregnancy complications and adverse pregnancy outcomes: a systematic review and meta-analysis
( BMJ Publishing Group , 2023 , Article)Background Adverse childhood experiences (ACEs) have a profound negative impact on health. However, the strength of the association between ACEs and pregnancy complications and adverse pregnancy outcomes is not well ... -
Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis
( BioMed Central , 2022 , Article)Background: Genetic variants within nearly 1000 loci are known to contribute to modulation of blood lipid levels. However, the biological pathways underlying these associations are frequently unknown, limiting understanding ... -
Date Palm Thorn Injury: A Literature Review and a Case Study of Extensive Hand Haematoma.
( Cureus , 2021 , Article)Date palm thorn injuries require a high level of clinical suspicion and careful management as they can lead to severe complications, such as tissue inflammation, synovitis, and extensive haematoma. Although it is associated ... -
A Modification to Enhance the Survival of the Island FDMA Flap by Adding a Skin Bridge
( national library of medicine , 2021 , Article)Background: Distal thumb injuries are common in high construction load regions, and it is a challenging task for the plastic surgeon to find the optimum choice that preserves thumb length and provides a sensory substitute ... -
Ovarian Dysgerminoma in Pregnant Women with Viable Fetus: A Rare Case Report
( karger , 2021 , Article)Dysgerminoma is an uncommon malignant tumor arising from the germ cells of the ovary. Its association with pregnancy is extremely rare, with a reported incidence of about 0.2-1 per 100,000 pregnancies. Women in the ... -
Dexamethasone induces the expression and function of tryptophan-2-3-dioxygenase in sk-mel-28 melanoma cells
( MDPI , 2021 , Article)Tryptophan-2,3-dioxygenase (TDO) is one of the key tryptophan-catabolizing enzymes with immunoregulatory properties in cancer. Contrary to expectation, clinical trials showed that inhibitors of the ubiquitously expressed ... -
Thrombosis Management and Challenges in COVID-19 Patients Presenting with Acute Coronary Syndromes.
( Medknow Publications , 2020 , Article)Thrombotic complications in patients with coronavirus disease 2019 (COVID-19) infection have been increasingly recognized, particularly those affecting the cardiovascular system. Patients with COVID-19 infection can suffer ... -
Racing for COVID-19 Vaccine and Cure: Lessons and Tragedies in Human Subject Research.
( Medknow Publications , 2020 , Article)Pressured by the enormous human and economic costs of the COVID-19 pandemic, certain countries and political figures have advocated the use of drugs and vaccines that did not go through the required regulatory stages of ... -
Characterizing the Qatar advanced-phase SARS-CoV-2 epidemic
( springer nature , 2021 , Article)The overarching objective of this study was to provide the descriptive epidemiology of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemic in Qatar by addressing specific research questions through a ... -
Doctors’ challenges during infectious disease outbreaks: Medical education insights from realistic fiction movies
( taylor and francis , 2021 , Article)Background: Movies have a strong influence on public perceptions due to their popularity and accessibility. Hence, movies on healthcare providers in general and medical doctors in particular can affect public opinions, ... -
Combination of Angiotensin (1-7) Agonists and Convalescent Plasma as a New Strategy to Overcome Angiotensin Converting Enzyme 2 (ACE2) Inhibition for the Treatment of COVID-19
( Frontiers , 2021 , Article)Coronavirus disease-2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is currently the most concerning health problem worldwide. SARS-CoV-2 infects cells by binding to ... -
Bibliometric analysis of adverse drug reactions and pharmacovigilance research activities in Nepal
( Sage , 2020 , Article)Background: Bibliometric analyses have been used previously to study the measures of quality and impact of research performed in several health-related areas such as adverse drug reactions (ADRs) and pharmacovigilance (PV), ... -
Morphometric Analysis of the Corpus Callosum According to Age and Sex in Middle Eastern Arabs: Racial Comparisons and Clinical Correlations to Autism Spectrum Disorder
( Frontiers Media S.A. , 2020 , Article)This study sought to examine the influence of age and sex on morphometric measurements of the corpus callosum (CC) within Middle Eastern Arab population, in order to obtain reference data and conduct racial comparisons ... -
Clinical characteristics of 51,815 patients presenting with positive and negative SARS-CoV-2 swab results in primary health care settings: Priority populations for vaccination
( Elsevier , 2021 , Article)We read with interest Brendish et al. study on the comparison between patients with SARS-CoV-2 positive and negative swab results.1 The study compared the clinical characteristics of adult hospitalised patients with ... -
Medical students’ perspectives on an assessment of reflective portfolios [response to letter]
( Dove Medical Press , 2020 , Other)We thank Forenc et al1 for their interest in our study titled Construct Validity of an Instrument for Assessment of Reflective Writing-Based Portfolios of Medical Students.2 In their Letter to Editor, their main critique ... -
Modulatory Effect of Intermittent Fasting on Adipose Tissue Inflammation: Amelioration of Cardiovascular Dysfunction in Early Metabolic Impairment
( Frontiers , 2021 , Article)Cardiometabolic syndrome (CMS) is a cluster of maladaptive cardiovascular, renal, thrombotic, inflammatory, and metabolic disorders. It confers a high risk of cardiovascular mortality and morbidity. CMS is triggered by ... -
Acute exposure to cigarette smoking followed by myocardial infarction aggravates renal damage in an in vivo mouse model
( Hindawi Limited , 2017 , Article)Cigarette smoking (S) is a risk factor for progressive chronic kidney disease, renal dysfunction, and renal failure. In this study, the effect of smoking on kidney function was investigated in a mouse model of myocardial ... -
Glycolytic overload-driven dysfunction of periodontal ligament fibroblasts in high glucose concentration, corrected by glyoxalase 1 inducer
( BMJ Publishing Group , 2020 , Article)Introduction Patients with diabetes have increased risk of periodontal disease, with increased risk of weakening of periodontal ligament and tooth loss. Periodontal ligament is produced and maintained by periodontal ligament ...
