Pharmacy Research: Recent submissions
Now showing items 121-140 of 1293
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Efficacy and tolerability of sulforaphane in the therapeutic management of cancers: a systematic review of randomized controlled trials
( Frontiers Media SA , 2023 , Article Review)Objectives: This paper presents a systematic review aimed at assessing the therapeutic potential of sulforaphane (SFN) in the treatment of diverse cancer types. Methods: Following Cochrane guidelines for systematic reviews, ... -
Emergency pharmacy workforce views and experience related to the provision of pharmaceutical care during mass gathering events: the FIFA World Cup Qatar 2022™ experience
( Frontiers Media SA , 2023 , Article)Purpose: This study aimed to explore emergency pharmacy workforce perspectives and experiences in providing pharmaceutical care during mass gathering events (i.e., FIFA World Cup Qatar 2022™). Methods: A qualitative ... -
The effectiveness and safety of palbociclib and ribociclib in stage IV HR+/HER-2 negative breast cancer: a nationwide real world comparative retrospective cohort study
( Frontiers Media SA , 2023 , Article)Introduction: Palbociclib and ribociclib are indicated in the first-line treatment of hormonal receptor-positive HER-2 negative (HR+/HER2- negative) advanced breast cancer. Although randomized-controlled trials (RCTs) ... -
Application of behavioural theories, models, and frameworks in pharmacy practice research based on published evidence: a scoping review
( Springer Science and Business Media Deutschland GmbH , 2024 , Article Review)Background: Pharmacy practice research often focuses on the design, implementation and evaluation of pharmacy services and interventions. The use of behavioural theory in intervention research allows understanding of ... -
Exploring the in vivo anti-cancer potential of Neosetophomone B in leukemic cells using a zebrafish xenograft model
( Elsevier Inc. , 2024 , Article)Neosetophomone B (NSP–B) is a unique meroterpenoid fungal secondary metabolite that has previously demonstrated promising anti-cancer properties against various cancer cell lines in vitro. However, its in vivo anti-cancer ... -
In vitro evaluation of Neosetophomone B inducing apoptosis in cutaneous T cell lymphoma by targeting the FOXM1 signaling pathway
( Elsevier , 2023 , Article)Background: Cutaneous T cell lymphoma (CTCL) is a T cell-derived non-Hodgkin lymphoma primarily affecting the skin, with treatment posing a significant challenge and low survival rates. Objective: In this study, we ... -
Nanoparticle-based materials in anticancer drug delivery: Current and future prospects
( Elsevier , 2023 , Article Review)The past decade has witnessed a breakthrough in novel strategies to treat cancer. One of the most common cancer treatment modalities is chemotherapy which involves administering anti-cancer drugs to the body. However, these ... -
Correction to: Beta-Caryophyllene Exhibits Anti-Proliferative Effects through Apoptosis Induction and Cell Cycle Modulation in Multiple Myeloma Cells (Cancers, (2021), 13, 22, (5741), 10.3390/cancers13225741)
( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article)In the original publication [1], errors were identified in the published Figures 4 and 7. The original raw data of western blots could not be retrieved and therefore the experiments were redone to generate the corrected ... -
Drug-Eluting Sutures by Hot-Melt Extrusion: Current Trends and Future Potentials
( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article Review)Surgical site infections (SSIs) may result from surgical procedures requiring a secondary administration of drugs at site or systemically in treating the infection. Drug-eluting sutures containing antimicrobial agents ... -
Docetaxel-Loaded Methoxy poly(ethylene glycol)-poly (L-lactic Acid) Nanoparticles for Breast Cancer: Synthesis, Characterization, Method Validation, and Cytotoxicity
( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article)This study aimed to synthesize and characterize DTX-mPEG-PLA-NPs along with the development and validation of a simple, accurate, and reproducible method for the determination and quantification of DTX in mPEG-PLA-NPs. The ... -
Patients' and primary carers' views on clozapine treatment for schizophrenia: A cross-sectional study in Qatar
( Elsevier , 2023 , Article)Subjective views of clozapine treatment among patients with schizophrenia in the Middle East and North African MENA Region have not previously been assessed. Globally, few studies have assessed the views of carers to ... -
Osmotic-driven release of papaverine hydrochloride from novel poly(decane-co-tricarballylate) elastomeric matrices
( Newlands Press Ltd , 2010 , Article)Background: We have recently reported on the synthesis, characterization and biocompatibility of a novel family of visible-light photocrosslinked poly(diol-co-tricarballylate) elastomers intended for use in drug delivery ... -
Novel poly (diol-co-tricarballylate) implantable elastomeric matrices: Long term biocompatibility and biodegradation studies
(2011 , Conference Paper)N/A. -
Soft biodegradable elastomers based on poly (octanediol-tartarate) for drug delivery and tissue engineering: Synthesis, characterization and biocompatibility studies
( Taylor & Francis , 2011 , Article)The synthesis, characterization and cytocompatibility of amorphous poly (octanediol-tartarate) thermoset biodegradable elastomeric polyesters are reported. The synthesis was achieved by preparing an aliphatic saturated ... -
Biocompatibility and biodegradability of implantable drug delivery matrices based on novel poly(decane-co-tricarballylate) photocured elastomers
( SAGE , 2012 , Article)Visible light photo-cross-linked biodegradable amorphous elastomers based on poly(decane-co-tricarballylate) (PDET) with different cross-linking densities were synthesized, and their cytotoxicity, biocompatibility, and ... -
Photo-irradiation paradigm: Mapping a remarkable facile technique used for advanced drug, gene and cell delivery
( Elsevier , 2015 , Article)Undoubtedly, the progression of photo-irradiation technique has provided a smart engineering tool for the state-of-the-art biomaterials that guide the biomedical and therapeutic domains for promoting the modern pharmaceutical ... -
Cultural Competence among Healthcare Professional Educators: A Mixed-Methods Study
( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article)As cultural diversity gains global prominence, healthcare professional educators (HPEs) are expected to exhibit a high level of cultural competence in education. Responding to this necessity requires the establishment of ... -
Clinical pharmacists’ interventions for preventing adverse events in critically ill neonates in Qatar: an economic impact analysis
( Springer Nature , 2024 , Article)Objective: This study aimed to assess the overall economic impact of clinical pharmacist interventions in the neonatal ICU (NICU) in Qatar. Methods: A retrospective review of neonates’ records was performed over a 3-month ... -
Inter-Varietal Variation in Phenolic Profile, Antioxidant, Anti-Inflammatory and Analgesic Activities of Two Brassica rapa Varieties: Influence on Pro-Inflammatory Mediators
( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article)The present research study aims to appraise the potential of polyphenol-rich extracts from two Brassica rapa varieties on antioxidant, anti-inflammatory and analgesic activities using carrageenan-induced paw edema model ...