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Human Papillomaviruses-Related Cancers: An Update on the Presence and Prevention Strategies in the Middle East and North African Regions.

Fernandes, Queenie; Allouch, Soumaya; Gupta, Ishita; Elmakaty, Ibrahim; Elzawawi, Khaled E; ... more authors ... less authors ( MDPI , 2022 , Article Review)

The human papillomavirus (HPV) is a non-enveloped double-stranded DNA virus capable of infecting skin and mucosa epithelial cells. Commonly, HPV infection is associated with sexually transmitted diseases and is considered ...

Quantification of the growth suppression of HER2+ breast cancer colonies under the effect of trastuzumab and PD-1/PD-L1 inhibitor.

Padmanabhan, Regina; Kheraldine, Hadeel; Gupta, Ishita; Meskin, Nader; Hamad, Anas; ... more authors ... less authors ( Frontiers Media , 2022 , Article)

Immune checkpoint blockade (ICB)-based therapy is revolutionizing cancer treatment by fostering successful immune surveillance and effector cell responses against various types of cancers. However, patients with HER2+ ...

Origanum syriacum L. Attenuates the Malignant Phenotype of MDA-MB231 Breast Cancer Cells

AlKahlout, Amal; Fardoun, Manal; Mesmar, Joelle; Abdallah, Rola; Badran, Adnan; ... more authors ... less authors ( Frontiers Media , 2022 , Article)

Breast cancer is the leading cause of cancer-related deaths among women. Among breast cancer types, triple negative breast cancer (TNBC) is the most aggressive, and is resistant to hormonal and chemotherapeutic treatments. ...

Ethanolic extract of Origanum syriacum L. leaves exhibits potent anti-breast cancer potential and robust antioxidant properties

Mesmar, Joelle; Abdallah, Rola; Hamade, Kamar; Baydoun, Serine; Al-Thani, Najlaa; ... more authors ... less authors ( Frontiers Media , 2022 , Article)

Background: Breast cancer (BC) is the second most common cancer overall. In women, BC is the most prevalent cancer and the leading cause of cancer-related mortality. Triple-negative BC (TNBC) is the most aggressive BC, ...

Fractionation and phytochemical composition of an ethanolic extract of Ziziphus nummularia leaves: antioxidant and anticancerous properties in human triple negative breast cancer cells

Abdallah, Rola; Shaito, Abdullah A.; Badran, Adnan; Baydoun, Serine; Sobeh, Mansour; ... more authors ... less authors ( Frontiers Media , 2024 , Article)

Natural products have long been utilized in traditional medicine as remedies to improve health and treat illnesses, and have had a key role in modern drug discovery. Recently, there has been a revived interest in the search ...

Ziziphus nummularia crude and fractionated extracts attenuate the malignant phenotype of human triple-negative breast cancer cells

Shaito, Abdullah; Abdallah, Rola; Sobeh, Mansour; Sahri, Nihad; Mesmar, Joelle E.; ... more authors ... less authors ( Symposium Cracoviense , 2024 , Conference Paper)

Triple negative breast cancer (TNBC) is the most aggressive subtype of breast cancer and has limited therapeutic options. Effects of Ziziphus nummularia against TNBC have not been investigated yet. An ethanolic extract of ...