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Now showing items 11-20 of 21
Genome-Wide Association Study Reveals a Novel Association Between MYBPC3 Gene Polymorphism, Endurance Athlete Status, Aerobic Capacity and Steroid Metabolism.
(
Frontiers Media
, 2020 , Article)
The genetic predisposition to elite athletic performance has been a controversial subject due to the underpowered studies and the small effect size of identified genetic variants. The aims of this study were to investigate ...
Alterations in Choline Metabolism in Non-Obese Individuals with Insulin Resistance and Type 2 Diabetes Mellitus
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2024 , Article)
The prevalence of non-obese individuals with insulin resistance (IR) and type 2 diabetes (T2D) is increasing worldwide. This study investigates the metabolic signature of phospholipid-associated metabolites in non-obese ...
Metabolomics and doping analysis: promises and pitfalls.
(
Future Science
, 2020 , Article)
This brief commentary presents an overview of the potential utility of metabolomics-based approaches in doping
analysis, with particular emphasis on areas where the current analytical procedures would most benefit from ...
Association between antioxidant metabolites and N-terminal fragment brain natriuretic peptides in insulin-resistant individuals.
(
Lippincott, Williams & Wilkins
, 2024 , Article)
Oxidative stress plays a pivotal role in the development of metabolic syndrome, including heart failure and insulin resistance. The N-terminal fragment of brain natriuretic peptide (NT-proBNP) has been associated with ...
Metabolic profiling of elite athletes with different cardiovascular demand
(
John Wiley & Sons Ltd
, 2019 , Article)
Intensive exercise of elite athletes can lead to physiological alterations in the cardiovascular system in response to increased stroke volume and blood pressure, known collectively as cardiovascular demand (CD). This study ...
Comparing Levels of Metabolic Predictors of Coronary Heart Disease between Healthy Lean and Overweight Females.
(
MDPI
, 2021 , Article)
Screening for the metabolomic signature of coronary heart disease (CHD) before disease onset could help in early diagnosis and potentially disease prevention. In this study, the levels of 17 CHD metabolic biomarkers in ...
The influence of circadian rhythm disruption during Ramadan on metabolic responses to physical activity: a pilot study
(
Frontiers Media SA
, 2025 , Article)
Background: Circadian rhythms and sleep patterns are important regulators of metabolic health. During Ramadan intermittent fasting (RIF), the sleep–wake cycles are often disrupted, which can affect physical activity (PA) ...
Enhancing Influenza Detection through Integrative Machine Learning and Nasopharyngeal Metabolomic Profiling: A Comprehensive Study
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2024 , Article)
Background/Objectives: Nasal and nasopharyngeal swabs are commonly used for detecting respiratory viruses, including influenza, which significantly alters host cell metabolites. This study aimed to develop a machine learning ...
Advancements in precision medicine: multi-omics approach for tailored metformin treatment in type 2 diabetes
(
Frontiers Media SA
, 2024 , Article Review)
Metformin has become the frontline treatment in addressing the significant global health challenge of type 2 diabetes due to its proven effectiveness in lowering blood glucose levels. However, the reality is that many ...
Metabolic signatures of combined exercise and fasting: an expanded perspective on previous telomere length findings
(
Frontiers Media SA
, 2024 , Article)
Introduction: Aging is a complex process marked by a gradual decline in physiological function and increased susceptibility to diseases. Telomere length is frequently regarded as one of the primary biomarkers of aging. ...