Biomedical Research Center Research: Recent submissions
Now showing items 241-260 of 840
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Editorial: Unconventional animal models in infectious disease research, volume II
( Frontiers Media , 2023 , Article)Infectious diseases remain a serious health threat globally, an actuality that necessitates ongoing research in this field. Among different research modalities, the use of animal models to unravel host-pathogen interactions ... -
A novel deep learning technique for morphology preserved fetal ECG extraction from mother ECG using 1D-CycleGAN
( Elsevier , 2024 , Article)The non-invasive fetal electrocardiogram (fECG) enables easy detection of developing heart abnormalities, leading to a significant reduction in infant mortality rate and post-natal complications. Due to the overlapping of ... -
Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals over 10 months
( Elsevier , 2023 , Article)BackgroundEvidence on the effectiveness of vaccination-induced immunity compared to SARS-CoV-2 natural immunity is warranted to inform vaccination recommendations. AimIn this study, we aimed to conduct a comparative ... -
Effects of previous infection, vaccination, and hybrid immunity against symptomatic Alpha, Beta, and Delta SARS-CoV-2 infections: an observational study
( Elsevier , 2023 , Article)BackgroundProtection against SARS-CoV-2 symptomatic infection and severe COVID-19 of previous infection, mRNA two-dose vaccination, mRNA three-dose vaccination, and hybrid immunity of previous infection and vaccination ... -
Enhancing the sensitivity of rapid antigen detection test (RADT) of different SARS-CoV-2 variants and lineages using fluorescence-labeled antibodies and a fluorescent meter
( Elsevier , 2023 , Article)RT-qPCR is considered the gold standard for diagnosis of COVID-19; however, it is laborious, time-consuming, and expensive. RADTs have evolved recently as relatively inexpensive methods to address these shortcomings, but ... -
Medicago orbicularis Has Antioxidant, Antihemolytic, and Anti-cancerous Activities and Augments Cisplatin-Induced Cytotoxicity in A549 Lung Cancer Cells
( preprints , 2023 , Article)Cancer is the second leading cause of death, worldwide. Lung cancer is the leading cause of cancer-related mortality. Plant-based therapeutics and herbal medicine have played a vital role in the development of several ... -
Editorial: Understanding Molecular Mechanisms in Diabetic Cardiomyopathy (DCM)
( Frontiers Media S.A. , 2022 , Article)Cardiovascular disease is the leading cause of death worldwide, and diabetes, the most common metabolic syndrome, causes a 2–5 times higher risk for heart disease (1). Specifically, cardiovascular complications in people ... -
Corrigendum: Association of Complement-Related Proteins in Subjects With and Without Second Trimester Gestational Diabetes (Front. Endocrinol., (2021), 12, (641361), 10.3389/fendo.2021.641361)
( Frontiers Media S.A. , 2021 , Article)In the original article, there was an error. One of the funders wasmissed out in the Acknowledgements. A correction has been made to the Acknowledgements section. “The authors would like to thank Qatar Metabolic Institute, ... -
The Effect of Chronic Endurance Exercise on Serum Levels of MOTS-c and Humanin in Professional Athletes
( IMR Press Limited , 2022 , Article)Background: Humanin and the mitochondrial open reading frame of the 12S rRNA-c (MOTS-c) are mitochondrial encoded peptides involved in energy metabolism, cytoprotection, longevity, insulin sensitivity and their expression ... -
Drug release kinetics from a drug-eluting stent with asymmetrical coat
( IMR Press Limited , 2017 , Article)The aim of this study was to investigate the drug release profiles of biodegradable polymer sirolimus- or paclitaxel-eluting stents with asymmetrical coating (BPSES-A or BPPES-A) both in vitro and in vivo. In vitro, the ... -
Molecular analysis of the enteric protozoa associated with acute diarrhea in hospitalized children
( Frontiers Media S.A. , 2017 , Article)Pediatric diarrhea is a common cause of death among children under 5 years of age. In the current study, we investigated the frequency of intestinal parasites among 580 pediatric patients with chronic diarrhea. Parasitic ... -
Biomaterials in Traumatic Brain Injury: Challenges and Perspectives
( Preprints , 2023 , Article Review)Traumatic brain injury (TBI) is among the leading causes of mortality and long-term impairment globally. TBI has a dynamic pathology encompassing a variety of metabolic and molecular events that occur in two phases, primary ... -
Exercise Metabolome: Insights for Health and Performance
( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article)Exercise has many benefits for physical and mental well-being. Metabolomics research has allowed scientists to study the impact of exercise on the body by analyzing metabolites released by tissues such as skeletal muscle, ... -
Latest Developments in Adapting Deep Learning for Assessing TAVR Procedures and Outcomes
( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article)Aortic valve defects are among the most prevalent clinical conditions. A severely damaged or non-functioning aortic valve is commonly replaced with a bioprosthetic heart valve (BHV) via the transcatheter aortic valve ... -
Internalization of metal-organic framework nanoparticles in human vascular cells: Implications for cardiovascular disease therapy
( Multidisciplinary Digital Publishing Institute (MDPI) , 2020 , Article)Cardiovascular diseases (CVDs) are the leading cause of morbidity and mortality worldwide. Alteration of endothelial cells and the underlying vasculature plays a central role in the pathogenesis of various CVDs. The ... -
The Spectrum of Antibiotic Prescribing during COVID-19 Pandemic: A Systematic Literature Review
( Mary Ann Liebert Inc. , 2021 , Article Review)Objectives: Over the last decades, there has been a significant increase in antimicrobial prescribing and consumption associated with the development of patients' adverse events and antimicrobial resistance (AMR) to the ... -
Applications of Machine Learning for Predicting Heart Failure
( Wiley , 2022 , Book chapter)Heart Failure is a major health burden for healthcare systems worldwide. Early diagnosis, prediction and management of patients with these conditions are critical to improve patient health outcome. The availability of large ... -
Minimally Invasive and Non-Invasive Technologies for Predicting Heart Failure
( Wiley , 2022 , Book chapter)Heart failure is a life-threatening medical problem which refers to inadequate blood supply to body tissues due to the limited functioning of heart muscles. Heart failure is mostly observed as a chronic disease which ... -
Unveiling a Biomarker Signature of Meningioma: the Need for a Panel of Genomic, Epigenetic, Proteomic, and RNA Biomarkers to Advance Diagnosis and Prognosis
( MDPI , 2023 , Unpublished Work)Meningiomas are the most prevalent primary intracranial tumors. The majority are benign but can undergo dedifferentiation in grades classified from I to III. Meningiomas tremendous variability in tumor behavior and slow ... -
Biochemical and cellular basis of oxidative stress: Implications for disease onset
( Wiley , 2023 , Article Review)Cellular oxidation–reduction (redox) systems, which encompass pro- and antioxidant molecules, are integral components of a plethora of essential cellular processes. Any dysregulation of these systems can cause molecular ...
