Biomedical Sciences: المرسلات الحديثة
السجلات المعروضة 401 -- 420 من 711
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Elaeagnus Angustifolia extract inhabits cell invasion of human colorectal cancer cells and increases the survival rate of the Drosophila colon cancer model
( Qatar University Press , 2021 , Poster)Colorectal cancer (CRC), the third most common type of cancer in the world, is an aggressive type of cancer with high tendency to metastasize and invade to other tissues and distant organs. Traditional CRC treatment regimen ... -
Development and In Vivo Testing of Smart Nanoparticles for Enhanced Anti-Cancer Activity and Reduced Cardiotoxicity Associated with Tyrosine Kinase Inhibitors
( Qatar University Press , 2021 , Poster)Tyrosine kinase inhibitors (TKIs) are new generation of anti-cancer drugs with very high efficiency against cancer cells. However, TKIs are associated with severe cardiotoxicity limiting their clinical benefits. One TKI ... -
Thrombotic and Hypercoagulability Complications of COVID-19: An Update
( Dovepress , 2021 , Article)The current COVID-19 pandemic emerged in December 2019, in China, affecting millions of people worldwide. COVID-19 is mainly a disease of the respiratory system, yet systematic complications have also been reported among ... -
Prevalence and risk factors of intestinal protozoan infection among symptomatic and asymptomatic populations in rural and urban areas of southern Algeria
( BMC , 2021 , Article)Intestinal parasitic infections are amongst the most common infections worldwide and have been identified as one of the most significant causes of morbidity and mortality among disadvantaged populations. This comparative ... -
Neutralization of MERS coronavirus through a scalable nanoparticle vaccine
( Springer Nature , 2021 , Article)MERS-CoV continues to cause human outbreaks, so far in 27 countries worldwide following the first registered epidemic in Saudi Arabia in 2012. In this study, we produced a nanovaccine based on virus-like particles (VLPs). ... -
COVID-19 Vaccine Hesitancy in a Representative Education Sector Population in Qatar
( MDPI , 2021 , Article)Even though vaccination programs have now started in earnest across the globe and in Qatar, vaccine hesitancy remains a barrier to effectively tackling the pandemic. Many factors influence willingness to take vaccines ... -
Knowledge Level, Motivators and Barriers of Blood Donation among Students at Qatar University
( MDPI , 2021 , Article)In Qatar, one out of every ten patients admitted to the hospitals is in urgent need of a blood transfusion or blood products. The aims of this study are as follows: (1) to assess the level of awareness and knowledge about ... -
Genetic polymorphisms associated with obesity in the Arab world: a systematic review
( Springer Nature , 2021 , Article Review)Background: Obesity, one of the most common chronic health conditions worldwide, is a multifactorial disease caused by complex genetic and environmental interactions. Several association studies have revealed a considerable ... -
Electroencephalographic evidence of gray matter lesions among multiple sclerosis patients: A case-control study.
( Lippincott, Williams & Wilkins , 2021 , Article)This study aimed to investigate evidence of gray matter brain lesions in multiple sclerosis (MS) patients by evaluating the resting state alpha rhythm of brain electrical activity.The study included 50 patients diagnosed ... -
Whole-Genome Sequencing for Molecular Characterization of Carbapenem-Resistant Enterobacteriaceae Causing Lower Urinary Tract Infection among Pediatric Patients
( MDPI , 2021 , Article)Antibiotic resistance is a growing public health problem globally, incurring health and cost burdens. The occurrence of antibiotic-resistant bacterial infections has increased significantly over the years. Gram-negative ... -
Can commercial automated immunoassays be utilized to predict neutralizing antibodies after SARS-CoV-2 infection? A comparative study between three different assays.
( IMR , 2021 , Article)Background: High-throughput assays that can infer neutralizing activity against SARS-CoV-2 are of great importance for assessing the immunity induced by natural infection and COVID-19 vaccines. We aimed to evaluate the ... -
Effect of multiple freeze–thaw cycles on the detection of anti-SARS- CoV- 2 IgG antibodies
( Microbiology Society , 2021 , Article)Several studies have investigated the effect of repeated freeze-thaw (F/T) cycles on RNA detection for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). However, no data are available regarding the effect of ... -
SARS-CoV-2 infection among primary healthcare workers: a cross- sectional study
( GERMS , 2021 , Article)Healthcare workers (HCWs) are critical to the healthcare system and are at an increased risk of SARS-CoV-2 infection. They may acquire infections from the community and their work settings. To date, the majority of the ... -
Zebrafish as a Model for Anticancer Nanomedicine Studies.
( MDPI , 2021 , Article Review)Nanomedicine is a new approach to fight against cancer by the development of anticancer nanoparticles (NPs) that are of high sensitivity, specificity, and targeting ability to detect cancer cells, such as the ability of ... -
Microbiota-derived acetate activates intestinal innate immunity via the Tip60 histone acetyltransferase complex
( Elsevier , 2021 , Article)Microbe-derived acetate activates the Drosophila immunodeficiency (IMD) pathway in a subset of enteroendocrine cells (EECs) of the anterior midgut. In these cells, the IMD pathway co-regulates expression of antimicrobial ... -
Fluid Flow Characteristics of Healthy and Calcified Aortic Valves Using Three-Dimensional Lagrangian Coherent Structures Analysis
( MDPI , 2021 , Article)Aortic valve calcification is an important cardiovascular disorder that deteriorates the accurate functioning of the valve leaflets. The increasing stiffness due to the calcification prevents the complete closure of the ... -
A review of novel coronavirus disease (COVID-19): based on genomic structure, phylogeny, current shreds of evidence, candidate vaccines, and drug repurposing
( Springer Verlag , 2021 , Article Review)Coronavirus disease (COVID-19) pandemic is instigated by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). As of March 13, 2021, more than 118.9 million cases were infected with COVID-19 worldwide. SARS-CoV-2 ... -
The prevalence of HEV among non-A-C hepatitis in Qatar and efciency of serological markers for the diagnosis of hepatitis E
( BMC , 2021 , Article)Background: The rapid growth of Qatar in the last two decades has attracted a large influx of immigrant workers who mostly come from HEV-hyperendemic countries. Thus, we aim to investigate the prevalence of HEV among acute ... -
Structure-Based Virtual Screening to Identify Novel Potential Compound as an Alternative to Remdesivir to Overcome the RdRp Protein Mutations in SARS-CoV-2.
( Frontiers Media , 2021 , Article)The number of confirmed COVID-19 cases is rapidly increasing with no direct treatment for the disease. Few repurposed drugs, such as Remdesivir, Chloroquine, Hydroxychloroquine, Lopinavir, and Ritonavir, are being tested ...