Biomedical Research Center: المرسلات الحديثة
السجلات المعروضة 1 -- 20 من 815
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Seroprevalence of Toxoplasma gondii in goats and sheep in Qatar
( Elsevier , 2025 , Article)BackgroundToxoplasmosis, caused by Toxoplasma gondii, is a zoonotic infection with significant implications for animal and human health. Congenital transmission leads to reproductive issues affecting livestock productivity. ... -
SEROPREVALENCE OF TOXOPLASMA GONDII AND ASSOCIATED RISK FACTORS IN ONE-HUMPED CAMELS (CAMELUS DROMEDARIUS) IN QATAR
(2025 , Article)Toxoplasma gondiii recognized as one of the most successful zoonotic parasites globally, infecting a wide range of hosts including camelids. This infection can lead to serious outcomes such as abortion, neonatal death, or ... -
The first insights into the gut microbiome profile of wild Mediterranean monk seal
( Springer Nature , 2025 , Article)Marine mammals (MMs) are crucial to the marine ecosystem, serving as apex predators, secondary consumers, and indicators of ocean health. Despite their ecological significance, human activities have greatly endangered many ... -
Advanced monolayer and layer-by-layer nanocapsule systems for sustained release of carvacrol and trans-cinnamaldehyde against multidrug-resistant Salmonella in poultry
( Springer Nature , 2025 , Article)Abstract: The rise of antibiotic-resistant Salmonella in poultry poses a significant public health challenge. This study assessed the efficacy of carvacrol and trans-cinnamaldehyde, in free and nanoencapsulated forms, as ... -
Clindamycin-resistant among Staphylococcus aureus: Investigation into phenotypic and genotypic profiles
( Public Library of Science , 2025 , Article)Background Antimicrobial resistance (AMR), particularly methicillin-resistant Staphylococcus aureus (MRSA), is a pressing global health concern. These bacteria are increasingly becoming resistant to the most commonly ... -
Silver-based dressings for the prevention of surgical site infections: evidence from randomized trials
( Elsevier , 2025 , Article)BackgroundSurgical site infections (SSIs) are a major cause of postoperative complications, increasing morbidity and healthcare costs. Silver-based dressings are commonly used due to their antimicrobial properties, but ... -
Defective ryanodine receptor N-terminus inter-subunit interaction is a common mechanism in neuromuscular and cardiac disorders
( Frontiers Media , 2022 , Article)The ryanodine receptor (RyR) is a homotetrameric channel mediating sarcoplasmic reticulum Ca<sup>2+</sup> release required for skeletal and cardiac muscle contraction. Mutations in RyR1 and RyR2 lead to life-threatening ... -
Disparate molecular mechanisms in cardiac ryanodine receptor channelopathies
( Frontiers Media , 2024 , Article)Aims: Mutations in the cardiac ryanodine receptor (RyR2) are associated with catecholaminergic polymorphic ventricular tachycardia (CPVT). This study investigates the underlying molecular mechanisms for CPVT mutations ... -
Centrifugal and Solution Blow Spinning Techniques in Tissue Engineering
( Bentham Science Publishers , 2024 , Book chapter)Nanofibers are a necessary source for fibrous materials and other useful applications such as tissue engineering, filtration, safety fabrics, batteries for the production of nanofibers so far. However, due to its low ... -
Exploring the link between environmental chemical exposures and epigenetic modifications in diabetes mellitus.
( The Association of Basic Medical Sciences , 2025 , Article Review)Diabetes mellitus (DM) is a globally prevalent metabolic disorder characterized by impaired glucose homeostasis and insulin secretion. Beyond traditional risk factors like lifestyle and genetics, environmental pollutants, ... -
Comprehensive analysis of human coronavirus antibody responses in ICU and non-ICU COVID-19 patients reveals IgG3 against SARS-CoV-2 spike protein as a key biomarker of disease severity
( Microbiology Society , 2025 , Article)Introduction. Pre-existing immunity to human coronaviruses (HCoVs) may shape the immune response in COVID-19 patients. Increasing evidence suggests that immune cross-reactivity between SARS-CoV-2 and other coronaviruses ... -
Antibody-dependent enhancement of SARS-CoV-2, the impact of variants and vaccination
( Taylor and Francis Group , 2025 , Article)This study characterized antibody-dependent enhancement (ADE) in serum samples from individuals exposed to SARS-CoV-2 via infection or vaccination and evaluated its association with SARS-CoV-2 variants (Wuhan and Omicron), ... -
The impact of pre-existing immunity on the emergence of within-host immune-escape mutations in Omicron lineages
( Microbiology Society , 2025 , Article)The Omicron variant of SARS-CoV-2 circulating amongst highly immunized populations is anticipated to induce immunological pressures, potentially compromising existing immunity. This study investigates vaccine-induced ... -
Glucosamine Schiff bases as fluorescent sensors for recognition of Al+3 and Zn+2 ions
( Elsevier , 2025 , Article)Glucosamine salicylidene (GAS) and Glucosamine-4-nitrosalicylidene (GANS) were synthesized using microwave and investigated as water-soluble chemosensors for aluminum and zinc ions. UV–vis, fluorescence titration, binding ... -
Medicinal Phytocompounds as Potential Inhibitors of p300-HIF1? Interaction: A Structure-Based Screening and Molecular Dynamics Simulation Study
( Multidisciplinary Digital Publishing Institute (MDPI) , 2025 , Article)Background: Hypoxia plays a key role in cancer progression, mainly by stabilizing and activating hypoxia-inducible factor-1 (HIF-1). For HIF-1 to function under low oxygen conditions, it must interact with the transcriptional ... -
Protection conferred by SARS-CoV-2 infection across a spectrum of reinfection symptoms and severities
( BMJ Publishing Group , 2025 , Article)Background SARS-CoV-2 infection is associated with protection against reinfection. This study analysed this protection across different reinfection symptoms and severities, comparing the preomicron and omicron eras. Methods ... -
N-Lactoyl amino acids as metabolic biomarkers differentiating low and high exercise response
( Institute of Sport , 2025 , Article)Aerobic physical exercise has significant benefits for cardiovascular health; however, some individuals experience no benefit or even adverse effects. One reason for poor tolerance to aerobic exercise may be a low percentage ... -
A Snapshot of Antimicrobial Resistance in Semi-Wild Oryx: Baseline Data from Qatar
( Multidisciplinary Digital Publishing Institute (MDPI) , 2025 , Article)Background/Objectives: The spread of antimicrobial resistance (AMR) is a growing global health concern. Wild animals can play an important role in the amplification and dissemination of AMR and in conservation efforts ... -
Accre 8 emerging point of care CLIA system for vitamin B12 assessment compared with three established assays
( Nature Research , 2025 , Article)Accurate Vitamin B12 (Vit B12) quantification is essential for diagnosing deficiencies linked to neurological and hematological disorders. The Accre 8 Point-of-Care (POC) Chemiluminescent Immunoassay (CLIA) system offers ... -
Indoleacetylglutamine Pathway Is a Potential Biomarker for Cardiovascular Diseases
( Multidisciplinary Digital Publishing Institute (MDPI) , 2025 , Article)Cardiovascular diseases (CVDs) remain a leading cause of global morbidity and mortality. Metabolomics allows for the identification of important biomarkers for CVDs, essential for early detection and risk assessment. This ...