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Reporting of RT-PCR cycle threshold (Ct) values during the first wave of COVID-19 in Qatar improved result interpretation in clinical and public health settings
(
Microbiology Society
, 2022 , Article)
Introduction. The cycle threshold (Ct) value in real-time PCR (RT-PCR) is where a target-specific amplification signal becomes detectable and can infer viral load, risk of transmission and recovery. Use of Ct values in ...
UNRAVELING THE MICROBIOME DIVERSITY AND DYNAMICS IN DIFFERENT SAMPLE TYPES DURING CORONAVIRUS INFECTIONS
(2024 , Master Thesis)
Background: Mucosal immunity and gut microbiome influence respiratory diseases like those caused by coronaviruses (HCoV). This study explores the relationship between HCoV infection and the respiratory and gut microbiome. ...
SARS-CoV-2 does not replicate in HaCaT spontaneously immortalized human keratinocytes: implications for the pathogenesis of COVID-19-associated skin manifestations
(
John Libbey Eurotext
, 2022 , Article)
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)-related cutaneous manifestations have been reported [1], however, the direct or indirect role of SARS-CoV-2 infection in their pathophysiology is still debated ...
NASAL EXPRESSION OF ANIOTENSIN-CONVERTING ENZYME 2 (ACE2) IN CHILDREN AND ADULTS WITH COVID-19
(2021 , Master Thesis)
"Emerging evidence suggests that the lower expression of SARS-CoV-2 entry factor angiotensin-converting enzyme 2 (ACE2) and transmembrane serine protease 2 (TMPRSS2) in the nasal epithelium of children may contribute to ...
Rapid Antibody-Based COVID-19 Mass Surveillance: Relevance, Challenges, and Prospects in a Pandemic and Post-Pandemic World.
(
MDPI
, 2020 , Article Review)
The aggressive outbreak of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) as COVID-19 (coronavirus disease-2019) pandemic demands rapid and simplified testing tools for its effective management. Increased ...
SARS-CoV-2 Infection and Smoking: What is the association? A brief review
(
Elsevier
, 2021 , Article)
Susceptibility to severe illness from COVID-19 is anticipated to be associated with cigarette smoking as it aggravates the risk of cardiovascular and respiratory illness, including infections. This is particularly important ...
D-Dimer Concentrations and COVID-19 Severity: A Systematic Review and Meta-Analysis
(
Frontiers Media
, 2020 , Article Review)
Coronavirus disease 2019 (COVID-19) is a recently described infectious disease caused
by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Since late 2019,
COVID-19 has rapidly spread in virtually all countries, ...
Comparison between nucleic acid amplification tests, antigen immunofluorescence assay, and in vitro infectivity in SARS-CoV-2 diagnosis.
(
Springer
, 2022 , Article)
The number of SARS-CoV-2 detection tests requested to the laboratories has dramatically increased together with an urgent need to release reliable responses in a very short time. The two options taken into consideration ...
Detection of SARS-CoV-2 RNA by direct RT-qPCR on nasopharyngeal specimens without extraction of viral RNA.
(
Public Library of Science
, 2020 , Article)
To circumvent the limited availability of RNA extraction reagents, we aimed to develop a protocol for direct RT-qPCR to detect SARS-CoV-2 in nasopharyngeal swabs without RNA extraction. Nasopharyngeal specimens positive ...
Seroprevalence of SARS-CoV2 in Qatar: a longitudinal epidemiological study
(
Qatar University Press
, 2020 , Poster)
In Qatar, the first COVID-19 cases were reported on the 29th of February 2020, and the numbers increased dramatically within few months. Primary Health Care Corporation in collaboration with Qatar University's Biomedical ...