تصفح Medicine Research حسب العنوان
السجلات المعروضة 765 -- 784 من 1354
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Life-threatening arrhythmogenic CaM mutations disrupt CaM binding to a distinct RyR2 CaM-binding pocket
( Elsevier , 2023 , Article)Calmodulin (CaM) modulates the activity of several proteins that play a key role in excitation-contraction coupling (ECC). In cardiac muscle, the major binding partner of CaM is the type-2 ryanodine receptor (RyR2) and ... -
Likelihood ratio interpretation of the relative risk
( BMJ Publishing Group , 2022 , Article)Interpreting diagnostic test results in medicine The likelihood ratio (LR) is today commonly used in medicine for diagnostic inference. Historically, it was preceded by introduction, in 1966, of the predictive value ... -
Linkages between poverty and food insecurity in Pakistan: Evidence from urban and rural households in Peshawar
( PROFESSIONAL MEDICAL PUBLICATIONS , 2023 , Article)Objective: To assess household poverty, sanitation and hygiene practices, and food security in both urban and rural settlements of district Peshawar. Methods: We conducted this cross-sectional study from March 2019 to ... -
Lipofibromatosis arising in a right labiocrural fold in a 14-month-old female: a case report study with a 3-year follow-up
( Oxford University Press , 2024 , Article)Lipofibromatosis (LF) is a rare benign fibrofatty tumor of infancy and childhood with a predilection for distal extremities, poor margination, and a high local recurrence rate. We report a toddler who presented with an LF ... -
Liraglutide treatment improves the coronary microcirculation in insulin resistant Zucker obese rats on a high salt diet.
( BMC , 2020 , Article)Obesity, hypertension and prediabetes contribute greatly to coronary artery disease, heart failure and vascular events, and are the leading cause of mortality and morbidity in developed societies. Salt sensitivity exacerbates ... -
Literature as a Pedagogical Tool in Medical Education: The Silent Patient Case
( Multidisciplinary Digital Publishing Institute (MDPI) , 2021 , Article)The arts have seen increasing use in medical education over the last 4 decades. Literature in particular is now frequently used as an educational tool in different medical humanities programmes. This paper analyses Alex ... -
Long Sun-Exposures Influencing High Sub-Cutaneous Synthesis of Vitamin-D3 may be Associated with Exacerbation of Symptoms in Allergic-Asthma.
(2018 , Article)Does excessive sun-exposure, non-use of sunscreen and/or high doses of vitamin-D3 supplements provoke exacerbation of asthma? Clinical examinations, retrospective records-access and questionnaire surveys were distributed ... -
A LONG-TERM 10G-HYPERGRAVITY EXPOSURE PROMOTES CELL-CELL CONTACTS AND REDUCES ADHESIVENESS TO A SUBSTRATE, MIGRATION, AND INVASIVENESS OF MCF-7HUMAN BREAST CANCER CELLS.
( Exp Oncol , 2022 , Article)G-force is a fundamental force controlling human cells. Cancer is one of the 4 major health challenges in the Space missions. Cancer in Space project evaluates the reaction of human cancer cells to the conditions of the ... -
Long-term in vivo study of biodegradable Zn-Cu stent: A 2-year implantation evaluation in porcine coronary artery
( Acta Materialia Inc , 2019 , Article)In the present study, a novel biodegradable Zn-0.8Cu coronary artery stent was fabricated and implanted into porcine coronary arteries for up to 24 months. Micro-CT analysis showed that the implanted stent was able to ... -
A Long-Term Outcome of the Patients with Sacrococcygeal Teratoma: A Bosnian Cohort
( AVES Ibrahim Kara , 2023 , Article)Objective: Sacrococcygeal teratoma is an extragonadal germ cell tumor that develops during fetal and neonatal periods and is associated with significant perinatal morbidity and even mortality. This study aimed to determine ... -
Lorcaserin vs. Phentermine among non-surgical and surgical obese patients: Anthropometric, glycemic, lipid, safety and cost outcomes
( Elsevier Ltd , 2019 , Article)Background To evaluate effectiveness, safety, and costs of Lorcaserin vs. phentermine among obese non–surgical and surgical patients (post bariatric surgery). Methods This retrospective study retrieved charts of all ... -
A low glycemic diet protects disease-prone Nrf2-deficient mice against age-related macular degeneration.
( Elsevier , 2020 , Article)Age-related macular degeneration (AMD) is a major blinding disease, affecting over 14% of the elderly. Risk for AMD is related to age, diet, environment, and genetics. Dietary modulation of AMD risk is a promising treatment ... -
Low levels of Vitamin D during pregnancy associated with gestational diabetes mellitus and low birth weight: results from the MAASTHI birth cohort
( Frontiers Media , 2024 , Article)Introduction: India has a high prevalence of Vitamin D insufficiency among women of childbearing age. In this study, we aimed to evaluate the potential relationship between Vitamin D deficiency and gestational diabetes ... -
Low risk of serological cross-reactivity between the dengue virus and SARS-CoV-2 IgG antibodies using advanced detection assays.
( Karger , 2022 , Report)Several studies have reported serological cross-reactivity of the immune responses between SARS-CoV-2 and DENV. Most of the available studies are based on the point of care (POC) rapid testing kits. However, some rapid ... -
Machine learning and discriminant function analysis in the formulation of generic models for sex prediction using patella measurements
( Springer Nature , 2022 , Article)Sex prediction from bone measurements that display sexual dimorphism is one of the most important aspects of forensic anthropology. Some bones like the skull and pelvis display distinct morphological traits that are based ... -
Macrophage responses associated with COVID-19: A pharmacological perspective
( Elsevier , 2020 , Article)COVID-19 has caused worldwide death and economic destruction. The pandemic is the result of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which has demonstrated high rates of infectivity leading to great ... -
Male infertility-linked point mutation reveals a vital binding role for the C2 domain of sperm PLC?
( Portland Press Ltd , 2017 , Article)Sperm-specific phospholipase C zeta (PLC?) is widely considered to be the physiological stimulus that evokes intracellular calcium (Ca2+) oscillations that are essential for the initiation of egg activation during mammalian ... -
Management of suicide and self-harm risk by the National Mental Health Helpline in the State of Qatar
( Cambridge University Press , 2023 , Article)Background Suicide is a serious public health problem. Aims To investigate the sociodemographic and clinical features of callers (patients) classed by the Qatar National Mental Health Helpline (NMHH) as moderate to high ... -
Mania and hypomania associated with COVID-19: a series of 15 cases seen by the consultation-liaison psychiatry service in Qatar
( Hamad bin Khalifa University Press (HBKU Press) , 2021 , Article)Background: A range of neuropsychiatric diagnoses have been reported in association with coronavirus disease 2019 (COVID-19). However, only sporadic cases of mania or hypomania have been reported in patients with COVID-19. ... -
Many meta-analyses of rare events in the Cochrane Database of Systematic Reviews were underpowered
( Elsevier , 2021 , Article)Background and ObjectiveMeta-analysis is a statistical method with the ability to increase the power for statistical inference, while it may still face the problem of being underpowered. In this study, we investigated the ...