Browsing Medicine Research by Title
Now showing items 352-371 of 1418
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Data reproducibility issues and their potential impact on conclusions from evidence syntheses of randomized controlled trials in sleep medicine
( Elsevier , 2022 , Article)In this study, we examined the data reproducibility issues in systematic reviews in sleep medicine. We searched for systematic reviews of randomized controlled trials published in sleep medicine journals. The metadata in ... -
Date Palm Thorn Injury: A Literature Review and a Case Study of Extensive Hand Haematoma.
( Cureus , 2021 , Article)Date palm thorn injuries require a high level of clinical suspicion and careful management as they can lead to severe complications, such as tissue inflammation, synovitis, and extensive haematoma. Although it is associated ... -
Death by suicide during COVID-19 infection: Two case reports
( HBKU Press , 2023 , Article)A range of psychiatric disorders has been recognized with coronavirus disease 2019 (COVID-19) infection, including acute stress, anxiety, depression, suicidal behavior, and post-traumatic stress disorder. Among those, the ... -
Decentralization of Mental Health Services in Qatar: A Promising Model for Enhancing Access and Optimizing Care
( Elsevier , 2021 , Other)In 2001, the World Health Organization (WHO) called for coordinated global efforts in reframing mental health agenda and broadening the conceptualization of mental disorders. A wider scope and better quality of service ... -
Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
( Elsevier , 2023 , Article)Mice with ectopic expression of uncoupling protein-1 (UCP1) in skeletal muscle exhibit a healthy aging phenotype with increased longevity and resistance to impaired metabolic health. This may be achieved by decreasing ... -
Decreased number of acute appendicitis cases in pediatric population during the COVID-19 pandemic: Any link?
( Elsevier , 2020 , Article)The reasons behind the decrease in AA frequency during the COVID-19 pandemic remain unclear. Some authors have proposed that milder forms can be treated conservatively at home [15] or using antibiotics. Snapiri et al. also ... -
Defective Interaction of Cam with RyR2 Cam-Binding Pocket Might Contribute to Arrhythmogenic Cardiac Disease
( Elsevier , 2020 , Article)Ryanodine receptor 2 (RyR2) is a large transmembrane calcium (Ca2+) release channel that mediates Ca2 release from the sarcoplasmic reticulum to activate cardiac muscle contraction. Calmodulin (CaM) regulation of RyR2 is ... -
DEFECTIVE NATURAL KILLER CELLS IN MELANOMA: ROLE OF NKG2D IN THE PATHOGENESIS AND IMMUNOTHERAPY
( Begell House , 2021 , Article)Melanoma is the most aggressive and deadliest form of skin cancer, and its prognosis is very poor. While the early detection is responsive to many treatments, metastatic melanoma is refractory to most of them. In the USA, ... -
A Delphi consensus study introducing a Problem And attRibutes‐bAsed DIabetes self‐manaGeMent (PARADIGM) intervention for patients with type 2 diabetes
( Elsevier , 2022 , Article)AimEncouraging patients to improve their self-management behavior based on a strict definition of the intervention is important for a standardized delivery but, until recently, there was no consensus on the core attributes ... -
Demographic and Clinical Characteristics of Early Travel-Associated COVID-19 Cases
( Frontiers Media , 2020 , Article)© Copyright © 2020 Marei, Emara, Elsaied, Nasrallah, Chivese, Al-Romaihi, Althani, Al Thani, Farag and Yassine. Background: SARS-CoV-2 continues to claim hundreds of thousands of people's lives. It mostly affects the elderly ... -
Demographic characteristics, laboratory features and complications in 346 cases of brucellosis: A retrospective study from Qatar
( Elsevier , 2024 , Article)Objectives: To study the epidemiology and laboratory findings and outcomes of human brucellosis in the state of Qatar. Methods: A retrospective study involving adult patients with a definitive diagnosis of brucellosis was ... -
Demographics and clinical characteristics of alcohol-related admissions in a tertiary care hospital in Qatar: Does age matter?
( Hamad bin Khalifa University Press (HBKU Press) , 2021 , Article)Background: Alcohol consumption is a major cause of acute and chronic health conditions associated with comorbidities and traumatic injuries, despite its partial prohibition in some countries. Moreover, alcohol-related ... -
Demystifying Smoker's Paradox: A Propensity Score-Weighted Analysis in Patients Hospitalized With Acute Heart Failure.
( Wiley Open Access , 2019 , Article)Background Smoker's paradox has been observed with several vascular disorders, yet there are limited data in patients with acute heart failure (HF). We examined the effects of smoking in patients with acute HF using data ... -
Dental implant placement with immersive technologies: A preliminary clinical report of augmented and mixed reality applications
( Elsevier , 2024 , Report)A preliminary clinical report of implant placements with 2 immersive reality technologies is described: augmented reality with head mounted display and mixed reality with a tablet PC. Both immersive realities are promising ... -
Deregulation of cell growth and apoptosis in UV-induced melanomagenesis
( Frontiers in Bioscience , 2020 , Article Review)We have previously characterized the role of p16/Rb in coordinating the early events in UVB-irradiated skin. As an extension to this work, normal melanocytes and mutant p16-inducible melanoma cell models were employed to ... -
Design, synthesis, and validation of novel nitrogen-based chalcone analogs against triple negative breast cancer
( Elsevier Masson s.r.l. , 2020 , Article)Great strides have been made in triple negative breast cancer (TNBC) treatment, which represents 20% of total predicted annual US breast cancer (BC) cases. Despite the development of several therapeutics, TNBC patients ... -
Detection of Antinuclear Antibodies Targeting Intracellular Signal Transduction, Metabolism, Apoptotic Processes and Cell Death in Critical COVID-19 Patients
( Universita Cattolica del Sacro Cuore , 2022 , Article)Background and Objectives: The heterogeneity of the coronavirus disease of 2019 (COVID-19) lies within its diverse symptoms and severity, ranging from mild to lethal. Acute respiratory distress syndrome (ARDS) is a leading ... -
Detection of β-Arrestin-Mediated G Protein-Coupled Receptor Ubiquitination Using BRET.
( Humana Press, New York, NY , 2019 , Book chapter)Ubiquitination of G protein-coupled receptors (GPCRs) is an important dynamic posttranslational modification that has been linked to the intracellular trafficking of internalized GPCRs to lysosomes. Ubiquitination of GPCRs ... -
Determinants of Atrial Fibrillation Development among Patients undergoing Ibrutinib Therapy
( Marshfield Clinic , 2022 , Article)Objective: Within the last decade, the use of ibrutinib, a first-generation, non-selective, irreversible Burton's tyrosine kinase inhibitor for the treatment of hematological malignancies has proven highly effective in ... -
The determination of causality of drug induced liver injury in patients with COVID-19 clinical syndrome
( Public Library of Science , 2022 , Article)Background Drug induced liver injury (DILI) is a rising morbidity amongst patients with COVID-19 clinical syndrome. The updated RUCAM causality assessment scale is validated for use in the general population, but its utility ...