Biomedical Research Center Research: Recent submissions
Now showing items 521-540 of 738
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Resveratrol Inhibits Oxidative Stress and Prevents Mitochondrial Damage Induced by Zinc Oxide Nanoparticles in Zebrafish (Danio rerio)
( MDPI , 2020 , Article)Despite their wide industrial use, Zinc oxide (ZnO) nanoparticles (NPs) exhibit a high toxic potential while concerns of their health-related risks are still present, urging additional in vivo clarification studies. ... -
Systematic Review of the Respiratory Syncytial Virus (RSV) Prevalence, Genotype Distribution, and Seasonality in Children from the Middle East and North Africa (MENA) Region
( MDPI , 2020 , Article)Respiratory syncytial virus (RSV) is one of the most common viruses to infect children worldwide and is the leading cause of lower respiratory tract illness (LRI) in infants. This study aimed to conduct a systematic review ... -
M cell targeting engineered biomaterials for effective vaccination
( Elsevier Ltd , 2019 , Article)Vaccines are one of the greatest medical interventions of all time and have been successful in controlling and eliminating a myriad of diseases over the past two centuries. Among several vaccination strategies, mucosal ... -
Growth factor releasing core-shell polymeric scaffolds for tissue engineering applications
( Institute of Electrical and Electronics Engineers Inc. , 2019 , Conference Paper)Tissue engineering is the use of a combination of cells, biomaterials and appropriate signals to repair or improve the functions of damaged tissues. Our group is exploiting various approaches to effectively encapsulate ... -
Graphene Oxide Loaded Hydrogel for Enhanced Wound Healing in Diabetic Patients
( Institute of Electrical and Electronics Engineers Inc. , 2019 , Conference Paper)Chronic wound or slow healing of a wound is one of the serious complications in diabetic patients. The decrease in the proliferation and migration of cells such as keratinocytes and fibroblasts is the major reason for the ... -
Development of titanium dioxide nanowire incorporated poly(vinylidene fluoride–trifluoroethylene) scaffolds for bone tissue engineering applications
( Springer New York LLC , 2019 , Article)Critical size bone defects that do not heal spontaneously are among the major reasons for the disability in majority of people with locomotor disabilities. Tissue engineering has become a promising approach for repairing ... -
Translating advances in organ-on-a-chip technology for supporting organs
( John Wiley and Sons Inc. , 2019 , Article Review)Organ‐on‐a‐chip platforms have recently seen tremendous progress. They have found potential applications in the study of physiology and pathology of tissues, drug toxicity, and development of tissue models for replacement ... -
Special appreciations are given to top five peer-reviewers of journal of food quality and hazards control in 2018
( Shahid Sadoughi University of Medical Sciences , 2019 , Article)[No abstract available] -
Nitric oxide releasing chitosan-poly (vinyl alcohol) hydrogel promotes angiogenesis in chick embryo model
( Elsevier B.V. , 2019 , Article)The lack of angiogenic activity is one of the serious complications of chronic wounds associated with delayed wound closure, chronic ulceration, and subsequent limb amputation. Multiple lines of evidence suggest that nitric ... -
Letrozole-loaded nonionic surfactant vesicles prepared via a slurry-based proniosome technology: Formulation development and characterization
( Elsevier , 2020 , Article)Slurry-based Letrozole (LTZ)-loaded proniosomes were designed using sucrose or sorbitol as carriers and various ratios of cholesterol (CH) and Tween 80 (T80) as lipid composition. Proniosomes were hydrated and probe-sonicated ... -
Identification and mapping of brain natriuretic peptide in the normal ventricular myocardium of a desert-dwelling mammalian model, the camel (Camelus dromedarius): Immunohistochemical and ultrastructural study
( Wiley-Liss Inc. , 2019 , Article)Brain natriuretic peptide (BNP) is mainly produced in the ventricular myocardium, where it is released into the circulation, producing rapid volume decrease by diuresis, natriuresis, and water shift into the extracellular ... -
Silver nanoparticle impregnated chitosan-PEG hydrogel enhances wound healing in diabetes induced rabbits
( Elsevier B.V. , 2019 , Article)Non-healing wounds are among the serious complications of type-2-diabetes around the globe, associated with high incidence of bacterial infection, chronic nerve and blood vessel damage, and eventually repeated amputation ... -
Long-term in vivo study of biodegradable Zn-Cu stent: A 2-year implantation evaluation in porcine coronary artery
( Acta Materialia Inc , 2019 , Article)In the present study, a novel biodegradable Zn-0.8Cu coronary artery stent was fabricated and implanted into porcine coronary arteries for up to 24 months. Micro-CT analysis showed that the implanted stent was able to ... -
Plasmonic gold nanoparticles: Optical manipulation, imaging, drug delivery and therapy
( Elsevier B.V. , 2019 , Article Review)Over the past two decades, the development of plasmonic nanoparticle (NPs), especially gold (Au) NPs, is being pursued more seriously in the medical fields such as imaging, drug delivery, and theranostic systems. However, ... -
The effect of aluminum oxide on red blood cell integrity and hemoglobin structure at nanoscale
( Elsevier B.V. , 2019 , Article)Herein, we explored the interaction of Al2O3 NPs with RBCs and Hb to determine the effect of Al2O3 NPs on hemolytic activity and Hb denaturation. The percentage of hemolysis of extracts and direct contact assays triggered ... -
Yttrium oxide nanoparticle loaded scaffolds with enhanced cell adhesion and vascularization for tissue engineering applications
( Elsevier Ltd , 2019 , Article)In situ tissue engineering is emerging as a novel approach in tissue engineering to repair damaged tissues by boosting the natural ability of the body to heal itself. This can be achieved by providing suitable signals and ... -
Advancing Frontiers in Bone Bioprinting
( Wiley-VCH Verlag , 2019 , Article Review)Three-dimensional (3D) bioprinting of cell-laden biomaterials is used to fabricate constructs that can mimic the structure of native tissues. The main techniques used for 3D bioprinting include microextrusion, inkjet, and ... -
The Implementation of an Integrated Management System at Qatar Biobank
( Mary Ann Liebert Inc. , 2019 , Article)Qatar Biobank (QBB) is a platform that will make vital health research possible through its collection of samples and information on health and lifestyle from the local population of Qatar. The goal of QBB is to collect, ... -
Albumin binding, antioxidant and antibacterial effects of cerium oxide nanoparticles
( Elsevier B.V. , 2019 , Article)Herein, the interaction of CeO2 NPs with HSA was explored by fluorescence, CD, UV–vis and molecular docking studies. Afterwards, the antioxidant activity of CeO2 NPs against H2O2-induced oxidative stress in BM-MSCs were ... -
Silymarin-albumin nanoplex: Preparation and its potential application as an antioxidant in nervous system in vitro and in vivo
( Elsevier B.V. , 2019 , Article)In this study, we formulated silymarin-HSA nanoplex and assayed its ability to reduce LPS-induced toxicity in vitro and in vivo. Silymarin molecules were encapsulated into HSA nanoplex and the loading efficiency and ...
