Browsing Biomedical Sciences by Title
Now showing items 43-62 of 687
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Antitumor Activities of the Novel Isosteviol Derivative 10C Against Liver Cancer
( International Institute of Anticancer Research , 2017 , Article)Background/Aim. Hepatocellular carcinoma (HCC) is the most common type of liver cancer and the fifth most common primary malignancy with worldwide increasing incidence. The current study aims to investigate the anticancer ... -
The Arab genome: Health and wealth
( Elsevier B.V. , 2016 , Article)The 22 Arab nations have a unique genetic structure, which reflects both conserved and diverse gene pools due to the prevalent endogamous and consanguineous marriage culture and the long history of admixture among different ... -
Arrhythmogenic calmodulin E105A mutation alters cardiac RyR2 regulation leading to cardiac dysfunction in zebrafish
( Wiley , 2019 , Article)Calmodulin (CaM) is a universal calcium (Ca )-binding messenger that regulates many vital cellular events. In cardiac muscle, CaM associates with ryanodine receptor 2 (RyR2) and regulates excitation-contraction coupling. ... -
Assessing the burden of intestinal parasites affecting newly arrived immigrants in Qatar
( BioMed Central , 2016 , Article)In the last decades, the enormous influx of immigrants to industrialized countries has led to outbreaks of parasitic diseases, with enteric infections being amongst the most frequently encountered. In its strategy to control ... -
Assessment of Broadly Reactive Responses in Patients With MERS-CoV Infection and SARS-CoV-2 Vaccination
( American Medical Association , 2023 , Article)Importance: In the ongoing COVID-19 pandemic, there remain unanswered questions regarding the nature and importance of the humoral immune response against other coronaviruses. Although coinfection of the Middle East ... -
Assessment of morphological changes due to oxidative stress: leukodepleted packed red blood cells stored in SAGM
( Canadian Society of Transfusion Medicine , 2016 , Conference Paper)Background: In blood bank, the storage procedures of packed red blood cell (pRBC) require some conditions to ensure the maximum storage time for a safe blood supply. pRBC can be stored up to 42 days in 2-6⁰C, as long as ... -
Assessment of the Neutralizing Antibody Response of BNT162b2 and mRNA-1273 SARS-CoV-2 Vaccines in Naïve and Previously Infected Individuals: A Comparative Study
( MDPI , 2022 , Report)The currently authorized mRNA COVID-19 vaccines, Pfizer-BNT162b2 and Moderna-mRNA-1273, offer great promise for reducing the spread of the COVID-19 by generating protective immunity against SARS-CoV-2. Recently, it was ... -
Association between Genetic Variants of GC Gene at 4q13.3 and Vitamin D Concentrations in Adult Females
( Longdom , 2019 , Article)Background: Vitamin D binding protein, encoded by the GC gene (on 4q13.3), plays an important role in transporting vitamin D. Several Genome-Wide Association Studies (GWASs) have established a significant association ... -
Association between Insulin and Nitric Oxide in Human Retinal Microvascular Endothelial Cells in vitro
( Hamad bin Khalifa University Press (HBKU Press) , 2016 , Conference Paper)Obesity and type 2 diabetes is characterized by insulin resistance which has been reported as the major risk factors associated with the development of the endothelial dysfunction and vascular complications such as ... -
The Association between Lifestyle Factors and COVID-19: Findings from Qatar Biobank.
( MDPI , 2024 , Article)Coronavirus Disease 2019 (COVID-19) manifestations range from mild to severe life-threatening symptoms, including death. COVID-19 susceptibility has been associated with various factors, but studies in Qatar are limited. ... -
Association between metabolically healthy obesity and metastasis in lung cancer patients – a systematic review and meta-analysis
( Frontiers Media , 2023 , Article Review)Background: Many clinical trials have looked at the relationship between obesity and lung cancer (LC), however, there is scarcity of literature specifically addressing the association between metabolically healthy obesity ... -
Association of adiponectin gene polymorphism (+T45G) with acute coronary syndrome and circulating adiponectin levels
( SAGE , 2012 , Article)We investigated the association of adiponectin gene polymorphisms (+T45G and +G276T) and adiponectin levels with acute coronary syndrome (ACS) among Arabs in Qatar. A case-control study was performed in 142 Arab patients ... -
Association of genetic variants with colorectal cancer in the extended MENA region: A systematic review
( Bentham Science Publishers , 2019 , Article)Colorectal cancer (CRC) is the third most common cancer worldwide and the third leading cause of cancer-related death. It is a heterogeneous disease that develops through different genetic and epigenetic mechanisms. To ... -
Association of Prior SARS-CoV-2 Infection With Risk of Breakthrough Infection Following mRNA Vaccination in Qatar.
( American Medical Association , 2021 , Article)The effect of prior SARS-CoV-2 infection on vaccine protection remains poorly understood. To assess protection from SARS-CoV-2 breakthrough infection after mRNA vaccination among persons with vs without prior SARS-CoV-2 ... -
Association of single nucleotide polymorphisms with dyslipidemia and risk of metabolic disorders in the State of Qatar
( Wiley-Blackwell , 2023 , Article)Background: Dyslipidemia is recognized as one of the risk factors of cardiovascular diseases (CVDs), type 2 diabetes mellitus (T2DM), and non-alcoholic fatty liver disease (NAFLD). Objective: The study aimed to investigate ... -
Association of Urinary Vitamin D-binding Protein and Megalin as Biomarkers for Diabetic Nephropathy in Type 2 Diabetes Mellitus in Qatari Patients
( OMICS , 2019 , Article)Abstract Background: Nephropathy is a common complication of type 2 diabetes mellitus (T2DM). Previous studies revealed that T2DM patients with nephropathy have higher concentrations of urinary Vitamin D Binding ... -
Association of Vitamin D Genetic Risk Score with Noncommunicable Diseases: A Systematic Review
( MDPI , 2023 , Article)Background and Aims: The genetic risk score (GRS) is an important tool for estimating the total genetic contribution or susceptibility to a certain outcome of interest in an individual, taking into account their genetic ... -
Associations of Vaccination and of Prior Infection with Positive PCR Test Results for SARS-CoV-2 in Airline Passengers Arriving in Qatar
( American Medical Association , 2021 , Other)The SARS-CoV-2 pandemic has severely affected international travel. With efficacious COVID-19 vaccines available, Qatar implemented a pilot program between February 18 and April 26, 2021, to ease travel restrictions by ... -
Associations of Vitamin D Receptor Polymorphism rs1544410 with Adiposity Phenotypes
( MedCrave , 2016 , Article)Background: Vitamin D receptor (VDR) is present on adipocytes, and many studies were performed to investigate the association between polymorphisms in VDR gene with obesity. However, in the Arab Gulf populations, whereas ... -
Attitudes and beliefs regarding the use of herbs and supplementary medications with COVID-19: A systematic review
( Elsevier , 2022 , Article)Background and aimThere is growing interest in using herbs and supplementary medications to treat and/or prevent COVID-19, evidenced by multiple reports exploring their effectiveness and safety. From a health psychology ...
