Apocrine Carcinoma
الملخص
Carcinoma with apocrine differentiation (invasive apocrine carcinoma) is defined by “WHO Classification
of Tumours of the Breast” as “any invasive carcinoma in which cells show the cytological features of apocrine cells” (O’Malley and Lakhani 2012). More strictly, it is a breast cancer characterized by apocrine morphology
(abundant eosinophilic and granular cytoplasm, centrally/eccentrically located nuclei with prominent
nucleoli and distinct cell borders) and a distinct steroid receptor profile: Estrogen receptor (ER)-negative and androgen receptor (AR)- positive cells (Vranic et al. 2013).
المجموعات
- أبحاث الطب [1418 items ]