Browsing Medicine Research by Author "Eid, Ali H."
Now showing items 21-40 of 92
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Covid-19 in pediatric patients: A focus on CHD patients
Zareef, Rana O.; Younis, Nour K.; Bitar, Fadi; Eid, Ali H.; Arabi, Mariam ( Frontiers Media S.A. , 2020 , Article)Coronavirus disease 2019 (COVID-19) is a global pandemic caused by SARS-CoV-2 virus. As of the 30th of September 2020, around 34,000,000 cases have been reported globally. Pediatrics with underlying congenital heart disease ... -
COVID-19: potential therapeutics for pediatric patients
Younis, Nour K.; Zareef, Rana O.; Fakhri, Ghina; Bitar, Fadi; Eid, Ali H.; Arabi, Mariam... more authors ... less authors ( Springer , 2021 , Article Review)The global spread of COVID-19 has imparted significant economic, medical, and social burdens. Like adults, children are affected by this pandemic. However, milder clinical symptoms are often experienced by them. Only a ... -
Cucurbituril Ameliorates Liver Damage Induced by Microcystis aeruginosa in a Mouse Model
Saleh, Na'il; Al-Jassabi, Saad; Eid, Ali H.; Nau, Werner M. ( Frontiers , 2021 , Article)Microcystis aeruginosa is a cyanobacterium that produces a variety of cyclic heptapeptide toxins in freshwater. The protective effects of the macromolecular container cucurbit[7]uril (CB7) were evaluated using mouse models ... -
Detection of Antinuclear Antibodies Targeting Intracellular Signal Transduction, Metabolism, Apoptotic Processes and Cell Death in Critical COVID-19 Patients
Nasarallah, Gheyath K.; Fakhroo, Aisha D.; Khan, Taushif; Cyprian, Farhan S.; Al Ali, Fatima; Ata, Manar M.A.; Taleb, Sara; Zedan, Hadeel T.; Al-Sadeq, Duaa W.; Amanullah, Fathima H.; Hssain, Ali A.; Eid, Ali H.; Abu-Raddad, Laith J.; Al-Khal, Abdullatif; Al Thani, Asmaa A.; Marr, Nico; Yassine, Hadi M.... more authors ... less authors ( Universita Cattolica del Sacro Cuore , 2022 , Article)Background and Objectives: The heterogeneity of the coronavirus disease of 2019 (COVID-19) lies within its diverse symptoms and severity, ranging from mild to lethal. Acute respiratory distress syndrome (ARDS) is a leading ... -
Dexamethasone Promotes a Stem-Like Phenotype in Human Melanoma Cells via Tryptophan 2,3 Dioxygenase
Cecchi, Marta; Mannini, Antonella; Lapucci, Andrea; Silvano, Angela; Lulli, Matteo; Luceri, Cristina; D’Ambrosio, Mario; Chiarugi, Alberto; Eid, Ali H.; Parenti, Astrid... more authors ... less authors ( Frontiers Media , 2022 , Article)In addition to its well-established immunosuppressive actions, tryptophan 2,3-dioxygenase (TDO) appears to elicit direct effects on tumor cell function. Although TDO has been associated with cancer stemness, its involvement ... -
Diagnostic Value of Non-invasive Liver Function Tests in Liver Fibrosis and Changes in These Parameters Post-metabolic Surgery
Jangjoo, Sara; Emami, Nima; Sahranavard, Mehrdad; Shah, Najeeb Z.; Alidadi, Mona; Baratzadeh, Fatemeh; Sathyapalan, Thozhukat; Eid, Ali H.; Jangjoo, Ali; Jamialahmadi, Tannaz; Sahebkar, Amirhossein... more authors ... less authors ( Springer , 2023 , Article)Purpose: This study aimed to ascertain the diagnostic accuracy of non-invasive liver function tests in liver fibrosis and assess their changes after metabolic surgery. Materials and Methods: 1005 individuals with severe ... -
Drug Repurposing in Vasculo-metabolic Diseases
Eid, Ali H. ( Bentham Science Publishers , 2023 , Other)Drug repurposing or repositioning is an approach that seeks to maximize the use of existing drugs by identifying new indications other than the ones for which the drug was initially conceived [1-5]. This approach has been ... -
Dysregulation of angiotensin converting enzyme 2 expression and function in comorbid disease conditions possibly contributes to coronavirus infectious disease 2019 complication severity
Hammoud, Safaa H.; Wehbe, Zena; Abdelhady, Samar; Kobeissy, Firas; Eid, Ali H.; El-Yazbi, Ahmed F.... more authors ... less authors ( American Society for Pharmacology and Experimental Therapy , 2021 , Article Review)ACE2 has emerged as a double agent in the COVID-19 ordeal, as it is both physiologically protective and virally conducive. The identification of ACE2 in as many as 72 tissues suggests that extrapulmonary invasion and damage ... -
Early metabolic impairment as a contributor to neurodegenerative disease: Mechanisms and potential pharmacological intervention
Fakih, Walaa; Zeitoun, Ralph; AlZaim, Ibrahim; Eid, Ali H.; Kobeissy, Firas; Abd-Elrahman, Khaled S.; El-Yazbi, Ahmed F.... more authors ... less authors ( Wiley , 2022 , Article Review)The metabolic syndrome comprises a family of clinical and laboratory findings, including insulin resistance, hyperglycemia, hypertriglyceridemia, low high-density lipoprotein cholesterol levels, and hypertension, in addition ... -
Editorial: Methods and application in cardiovascular and smooth muscle pharmacology: 2021
El-Yazbi, Ahmed F.; Eid, Ali H.; Zouein, Fouad A.; Abd-Elrahman, Khaled S. ( Frontiers Media S.A. , 2022 , Other)Despite significant advances in basic, translational, and clinical research tackling heart disease, cardiovascular pathologies remain among the leading causes of mortality and morbidity worldwide, being responsible for ... -
Effect of Bariatric Surgery on Serum Amyloid A Protein: a Systematic Review and Meta-analysis
Jamialahamdi, Tannaz; Mirhadi, Elaheh; Atkin, Stephen L.; le Roux, Carel W.; Kroh, Matthew; Almahmeed, Wael; Eid, Ali H.; Sahebkar, Amirhossein... more authors ... less authors ( springer link , 2023 , Article)Background: Obesity is a chronic inflammatory condition and this meta-analysis evaluated the impact of bariatric surgery on SAA. Methods: Studies included all types of bariatric surgery where SAA was measured before and ... -
Effect of BPA on CYP450s expression, and nicotine modulation, in fetal rat brain
Mohammad H., Merii; Fardoun, Manal M.; El Asmar, Khalil; Khalil, Mahmoud I.; Eid, Ali H.; Dhaini, Hassan R.... more authors ... less authors ( Elsevier , 2022 , Article)Human exposure to bisphenol A (BPA) is mainly due to migration from plastic packaging into food and beverages. Studies reported BPA endocrine disruptions through interactions with different nuclear receptors, including the ... -
The effect of nuts consumption on circulating oxidized low-density lipoproteins: A systematic review and meta-analysis of randomized controlled trials.
Abbasifard, Mitra; Jamialahmadi, Tannaz; Reiner, Željko; Eid, Ali H; Sahebkar, Amirhossein ( Wiley , 2023 , Article Review)This systematic review and meta-analysis evaluated the effect of nuts in decreasing circulating levels of oxidized low-density lipoproteins (ox-LDL). A literature search was performed of major electronic databases ... -
Effect of Resveratrol on Pregnancy, Prenatal Complications and Pregnancy-Associated Structure Alterations.
Ramli, Iman; Posadino, Anna Maria; Giordo, Roberta; Fenu, Grazia; Fardoun, Manal; Iratni, Rabah; Eid, Ali H; Zayed, Hatem; Pintus, Gianfranco... more authors ... less authors ( MDPI , 2023 , Article Review)Adverse pregnancy outcomes are considered significant health risks for pregnant women and their offspring during pregnancy and throughout their lifespan. These outcomes lead to a perturbated in-utero environment that impacts ... -
Effect of statins on abdominal aortic aneurysm
Azar, Hosseini; Sahranavard, Toktam; Reiner, Željko; Jamialahmadi, Tannaz; Dhaheri, Yusra Al; Eid, Ali H.; Sahebkar, Amirhossein... more authors ... less authors ( Elsevier , 2022 , Article Review)Abdominal aortic aneurysm (AAA) is a prevalent condition which causes progressive growth and rupture of aortic wall with a high death rate. Several studies have found that treatment with statins may decrease the progress ... -
Effects of a single dose of ivermectin on viral and clinical outcomes in asymptomatic sars-cov-2 infected subjects: A pilot clinical trial in lebanon
Samaha, Ali A.; Mouawia, Hussein; Fawaz, Mirna; Hassan, Hamad; Salami, Ali; Bazzal, Ali A.; Saab, Hamid B.; Al-Wakeel, Mohamed; Alsaabi, Ahmad; Chouman, Mohamad; Moussawi, Mahmoud A.; Ayoub, Hassan; Raad, Ali; Hajjeh, Ola; Eid, Ali H.; Raad, Houssam... more authors ... less authors ( MDPI , 2021 , Article)Objective: This study was designed to determine the efficacy of ivermectin, an FDA-approved drug, in producing clinical benefits and decreasing the viral load of SARS-CoV-2 among asymptomatic subjects that tested positive ... -
The Effects of Statin Treatment on Serum Ferritin Levels: A Systematic Review and Meta-Analysis
Jamialahmadi, Tannaz; Abbasifard, Mitra; Reiner, Željko; Rizzo, Manfredi; Eid, Ali H.; Sahebkar, Amirhossein... more authors ... less authors ( Multidisciplinary Digital Publishing Institute (MDPI) , 2022 , Article)Background: Statins are the most widely used drugs for decreasing elevated serum LDL-cholesterol (LDL-C) and thus for the prevention of atherosclerotic cardiovascular disease (ASCVD), but they have also some pleiotropic ... -
Effects of Trehalose Administration in Patients with Mucopolysaccharidosis Type III.
Mobini, Moein; Radbakhsh, Shabnam; Kubaski, Francyne; Eshraghi, Peyman; Vakili, Saba; Vakili, Rahim; Abbasifard, Mitra; Jamialahmadi, Tannaz; Rajabi, Omid; Emami, Seyed Ahmad; Tayarani-Najaran, Zahra; Rizzo, Manfredi; Eid, Ali H; Banach, Maciej; Sahebkar, Amirhossein... more authors ... less authors ( Europe PMC , 2023 , Article)Mucopolysaccharidosis type III (MPS III) is a rare autosomal recessive lysosomal storage disease (LSD) caused by a deficiency of lysosomal enzymes required for the catabolism of glycosaminoglycans (GAGs), mainly in the ... -
Epac as a tractable therapeutic target
Hasan, Slika; Mansour, Hadi; Nasser, Suzanne A.; Shaito, Abdullah; Kobeissy, Firas; Orekhov, Alexander N.; Pintus, Gianfranco; Eid, Ali H.... more authors ... less authors ( Elsevier , 2023 , Article)In 1957, cyclic adenosine monophosphate (cAMP) was identified as the first secondary messenger, and the first signaling cascade discovered was the cAMP-protein kinase A (PKA) pathway. Since then, cAMP has received increasing ... -
Exploring serum glycome patterns after moderate to severe traumatic brain injury: A prospective pilot study
Stefania, Mondello; Sandner, Viktor; Goli, Mona; Czeiter, Endre; Amrein, Krisztina; Kochanek, Patrick M.; Gautam, Sakshi; Cho, Byeong Gwan; Morgan, Ryan; Nehme, Ali; Fiumara, Giacomo; Eid, Ali H.; Barsa, Chloe; Haidar, Muhammad Ali; Buki, Andras; Kobeissy, Firas H.; Mechref, Yehia... more authors ... less authors ( Elsevier , 2022 , Article)BackgroundGlycans play essential functional roles in the nervous system and their pathobiological relevance has become increasingly recognized in numerous brain disorders, but not fully explored in traumatic brain injury ...