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Comprehensive genomic profiling of a metastatic small cell lung carcinoma with a complete and long-term response to atezolizumab: A case report
(
Elsevier
, 2023 , Article)
Small cell lung cancer (SCLC) is a highly aggressive malignancy with a poor outcome. We present the case of a 57-year-old male patient with extensive-stage (ES-SCLC) treated with chemotherapy and atezolizumab. A complete ...
Development of an evidence-based model for predicting patient, provider, and appointment factors that influence no-shows in a rural healthcare system
(2023 , Article)
Background: No-show appointments pose a significant challenge for healthcare providers, particularly in rural areas. In this study, we developed an evidence-based predictive model for patient no-shows at the Marshfield ...
Editorial: Global excellence in children and health
(
springer link
, 2023 , Other)
Cooperation and collaboration within and between countries is an increasingly important component of tackling and overcoming the pressing issues impacting upon children's health and wellbeing. This Research Topic (RT) aimed ...
Effect of Bariatric Surgery on Serum Amyloid A Protein: a Systematic Review and Meta-analysis
(
springer link
, 2023 , Article)
Background: Obesity is a chronic inflammatory condition and this meta-analysis evaluated the impact of bariatric surgery on SAA. Methods: Studies included all types of bariatric surgery where SAA was measured before and ...
IP3 receptors: An "elementary" journey from structure to signals
(
Elsevier
, 2023 , Article)
Inositol 1,4,5-trisphosphate receptors (IP3Rs) are large tetrameric channels which sit mostly in the membrane of the endoplasmic reticulum (ER) and mediate Ca2+ release from intracellular stores in response to extracellular ...
RamanNet: a generalized neural network architecture for Raman spectrum analysis
(
Springer Science and Business Media Deutschland GmbH
, 2023 , Article)
Raman spectroscopy provides a vibrational profile of the molecules and thus can be used to uniquely identify different kinds of materials. This sort of molecule fingerprinting has thus led to the widespread application of ...
Thermogenic Modulation of Adipose Depots: A Perspective on Possible Therapeutic Intervention with Early Cardiorenal Complications of Metabolic Impairment
(
American Society for Pharmacology and Experimental Therapy (ASPET)
, 2023 , Article)
Cardiovascular complications of diabetes and obesity remain a major cause for morbidity and mortality worldwide. Despite significant advances in the pharmacotherapy of metabolic disease, the available approaches do not ...
The attitude and knowledge of pediatricians and family physicians toward COVID-19 vaccination in children: A cross-sectional study
(
Taylor and Francis Ltd.
, 2023 , Article)
COVID-19 vaccines to children are expected to reduce the transmission of the disease to high-risk groups and achieve herd immunity in younger populations. A positive attitude toward COVID-19 vaccination in children among ...
GPER Acts Through the cAMP/Epac/JNK/AP-1 Pathway to Induce Transcription of Alpha 2C Adrenoceptor in Human Microvascular Smooth Muscle Cells
(
Wolters Kluwer Health
, 2023 , Article)
Raynaud's phenomenon, which results from exaggerated cold-induced vasoconstriction, is more prevalent in females than males. We previously showed that estrogen increases the expression of alpha 2C-adrenoceptors (α2C-AR), ...
The Effects of Statin Therapy on Circulating Levels of Trimethylamine N-oxide: A Systematic Review and Meta-analysis
(
Bentham Science Publishers
, 2023 , Article)
Background
Gut microbiota is associated with an increased risk of atherosclerotic cardiovascular disease (ASCVD) through the metabolites, which can induce atherogenesis. One of these metabolites is trimethylamine N-oxide ...