Medicine Research: المرسلات الحديثة
السجلات المعروضة 1361 -- 1380 من 1739
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Laplace approximation, penalized quasi-likelihood, and adaptive Gauss-Hermite quadrature for generalized linear mixed models: Towards meta-analysis of binary outcome with sparse data
( BMC , 2020 , Article)© 2020 The Author(s). Background: In meta-analyses of a binary outcome, double zero events in some studies cause a critical methodology problem. The generalized linear mixed model (GLMM) has been proposed as a valid ... -
Protocols for meta-analysis of intervention safety seldom specified methods to deal with rare events
( Elsevier , 2020 , Article Review)ObjectivesMeta-analyses of rare events often generate unstable results, and selective reporting of the results may mislead the health care decision. Developing a synthesis plan for rare events in protocol may help to ... -
Methodological issues of systematic reviews and meta-analyses in the field of sleep medicine: A meta-epidemiological study
( Elsevier , 2021 , Article)An increasing number of systematic reviews and meta-analyses (SRMAs) have been published in the field of sleep medicine. We evaluated the methodological issues of these SRMAs. A protocol was developed in advance. Three ... -
Association between response rates and monetary incentives in sample study: a systematic review and meta-analysis.
( BMJ Publishing Group , 2020 , Article)To investigate the effect of monetary incentive and the dose-response relationship of participants' response rates in surveys. Three databases were searched for randomised controlled trials (RCTs) that investigated the ... -
Many meta-analyses of rare events in the Cochrane Database of Systematic Reviews were underpowered
( Elsevier , 2021 , Article)Background and ObjectiveMeta-analysis is a statistical method with the ability to increase the power for statistical inference, while it may still face the problem of being underpowered. In this study, we investigated the ... -
Arcsine-based transformations for meta-analysis of proportions: Pros, cons, and alternatives
( Wiley Open Access , 2020 , Article)© 2020 The Authors. Health Science Reports published by Wiley Periodicals LLC. Meta-analyses have been increasingly used to synthesize proportions (eg, disease prevalence) from multiple studies in recent years. Arcsine-based ... -
Unexpected adrenal pheochromocytoma associated with a generalized tonic-clonic seizure in a prepubertal boy: A case report.
( Lippincott, Williams & Wilkins , 2021 , Article)Pheochromocytoma (PHEO) is a rare neuroendocrine tumor arising from chromaffin cells of the adrenal medulla. Most pediatric PHEOs are functional tumors, and clinical manifestations are related to catecholamine hypersecretion ... -
Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale
( Nature Research , 2020 , Article)Large-scale whole-genome sequencing studies have enabled the analysis of rare variants (RVs) associated with complex phenotypes. Commonly used RV association tests have limited scope to leverage variant functions. We propose ... -
Transethnic Transferability of a Genome-wide Polygenic Score for Coronary Artery Disease.
( American Heart Association , 2020 , Article)N/A -
Genome-wide polygenic score, clinical risk factors, and long-term trajectories of coronary artery disease
( American Heart Association , 2020 , Article)OBJECTIVE: To determine the relationship of a genome-wide polygenic score for coronary artery disease (GPSCAD) with lifetime trajectories of CAD risk, directly compare its predictive capacity to traditional risk factors, ... -
Blood pressure and bladder cancer risk in men by use of survival analysis and in interaction with NAT2 genotype, and by Mendelian randomization analysis
( Public Library of Science , 2020 , Article)The association between blood pressure (BP) and bladder cancer (BC) risk remains unclear with confounding by smoking being of particular concern. We investigated the association between BP and BC risk among men using ... -
The MethodologicAl STandards for Epidemiological Research (MASTER) scale demonstrated a unified framework for bias assessment
( Elsevier , 2021 , Article)Objective: This paper presents a unified framework for assessment of the methodological quality of analytic study designs. Study Design and Setting: A systematic review of 393 methodological quality assessment tools that ... -
Country and gender-specific achievement of healthy nutrition and physical activity guidelines: Latent class analysis of 6266 university students in Egypt, Libya, and Palestine
( MDPI AG , 2017 , Article)Research on healthy behaviour such as physical activity and healthy nutrition and their combination is lacking among university students in Arab countries. The current survey assessed healthy nutrition, and moderate/vigorous ... -
Diagnostic Efficiency of Three Fully Automated Serology Assays and Their Correlation with a Novel Surrogate Virus Neutralization Test in Symptomatic and Asymptomatic SARS-COV-2 Individuals
( MDPI , 2020 , Article)Abstract: To support the deployment of serology assays for population screening during the COVID-19 pandemic, we compared the performance of three fully automated SARS-CoV-2 IgG assays: Mindray CL-900i® (target: spike [S] ... -
Dishevelled family proteins (DVL1-3) expression in intrauterine growth restriction (IUGR) placentas.
( BJBMS , 2020 , Article)Dishevelled family proteins (DVL1, DVL2, and DVL3) are cytoplasmic proteins that are involved in canonical and non-canonical Wnt signaling pathway during embryonic development. The role of DVL proteins in the placental ... -
Immunogenicity after pre- and post-exposure rabies vaccination: A systematic review and dose-response meta-analysis
( Elsevier , 2021 , Article)There are a myriad of vaccine schedules for rabies pre- (PrEP) and post-exposure prophylaxis (PEP) that differ in the number and timedoses, number of visits, length of schedule, and route of administration. The objective ... -
Cellular and molecular targets of menthol actions
( Frontiers Media S.A. , 2017 , Article Review)Menthol belongs to monoterpene class of a structurally diverse group of phytochemicals found in plant-derived essential oils. Menthol is widely used in pharmaceuticals, confectionary, oral hygiene products, pesticides, ... -
High-risk human papillomaviruses and epstein-barr virus presence and crosstalk in human oral carcinogenesis
( Springer International Publishing , 2017 , Book chapter)Oral cancer is the most frequent type of malignancy of the head and neck area worldwide. This cancer is a major cause of mortality in several parts of the world especially in certain Asian countries. In fact, the majority ... -
Role of Qat chewing and mate consumption in human oral carcinogenesis
( Springer International Publishing , 2017 , Book chapter)[No abstract available] -
Development of oral cancer: Risk factors and prevention strategies
( Springer International Publishing , 2017 , Book)This book aims to provide the reader with a complete understanding of the development of oral cancer by explaining the role of a wide variety of implicated risk factors and identifying their gene targets and key regulators. ...
