Browsing Biomedical Research Center Research by Title
Now showing items 71-90 of 724
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Bacterial indoor air contaminations in hospitals in MENA region: a systematic review
( Taylor and Francis , 2022 , Article Review)Poor indoor air quality in healthcare settings has been tied with the increase in hospital-acquired infections. Thus, this systematic review was conducted to assess the levels and compositions of bacteria in indoor hospital ... -
Bio-vehicles of cytotoxic drugs for delivery to tumor specific targets for cancer precision therapy
( Elsevier , 2021 , Article Review)Abnormal structural and molecular changes in malignant tissues were thoroughly investigated and utilized to target tumor cells, hence rescuing normal healthy tissues and lowering the unwanted side effects as non-specific ... -
Bioactive scaffold (sodium alginate)-g-(nHAp@SiO2@GO) for bone tissue engineering
( Elsevier , 2022 , Article)Globally, people suffering from bone disorders are steadily increasing and bone tissue engineering is an advanced approach to treating fractured and defected bone tissues. In this study, we have prepared polymeric nanocomposite ... -
Biochemical and cellular basis of oxidative stress: Implications for disease onset
( Wiley , 2023 , Article Review)Cellular oxidation–reduction (redox) systems, which encompass pro- and antioxidant molecules, are integral components of a plethora of essential cellular processes. Any dysregulation of these systems can cause molecular ... -
Biochemical and structural impact of two novel missense mutations in cystathionine β-synthase gene associated with homocystinuria
( Portland Press Ltd , 2024 , Article)Homocystinuria is a rare disease caused by mutations in the CBS gene that results in a deficiency of cystathionine β-synthase (CBS). CBS is an essential pyridoxal 50-phosphate (PLP)-dependent enzyme in the transsulfuration ... -
Biocompatibility and toxicity of novel iron chelator Starch-Deferoxamine (S-DFO) compared to zinc oxide nanoparticles to zebrafish embryo: An oxidative stress based apoptosis, physicochemical and neurological study profile.
( Elsevier , 2019 , Article)Clinically approved iron chelators are effective in decreasing significant transfusional iron accumulation. Starch-Deferoxamine (S-DFO), a novel high molecular weight iron chelator, was produced to increase binding capacity ... -
Biological applications of imiquimod analogues: An update (Review)
( Spandidos Publications , 2023 , Article Review)The last decade witnessed intensive efforts in drug discovery and the emergence of thousands of molecules with potential for use as therapeutic targets. However, only a few hundred of these molecules reached the stage of ... -
Biomaterials in Traumatic Brain Injury: Challenges and Perspectives
( Preprints , 2023 , Article Review)Traumatic brain injury (TBI) is among the leading causes of mortality and long-term impairment globally. TBI has a dynamic pathology encompassing a variety of metabolic and molecular events that occur in two phases, primary ... -
Biomaterials in Traumatic Brain Injury: Perspectives and Challenges
( MDPI , 2023 , Article Review)Traumatic brain injury (TBI) is a leading cause of mortality and long-term impairment globally. TBI has a dynamic pathology, encompassing a variety of metabolic and molecular events that occur in two phases: primary and ... -
Biomechanical Investigation of Disturbed Hemodynamics-Induced Tissue Degeneration in Abdominal Aortic Aneurysms Using Computational and Experimental Techniques.
( Frontiers Media , 2019 , Article Review)Abdominal aortic aneurysm (AAA) is the dilatation of the aorta beyond 50% of the normal vessel diameter. It is reported that 4-8% of men and 0.5-1% of women above 50 years of age bear an AAA and it accounts for ~15,000 ... -
Blood Flow Disturbance and Morphological Alterations Following the Right Atrial Ligation in the Chick Embryo.
( Frontiers Media , 2022 , Article)Collectively known as congenital heart defects (CHDs), cardiac abnormalities at birth are the most common forms of neonatal defects. Being principally responsible for the heart's pumping power, ventricles are particularly ... -
BNT162b2 and mRNA-1273 COVID-19 vaccine effectiveness against the SARS-CoV-2 Delta variant in Qatar.
( Nature Researc , 2021 , Article)With the global expansion of the highly transmissible SARS-CoV-2 Delta (B.1.617.2) variant, we conducted a matched test-negative case-control study to assess the real-world effectiveness of COVID-19 messenger RNA vaccines ... -
BNT162b2 antigen dose and SARS-CoV-2 omicron infection in adolescents
( Elsevier , 2023 , Other)COVID-19 vaccine antigen dose might affect protection against SARS-CoV-2 infection,1, 2 but direct evidence to quantify this effect is absent. We conducted a matched, retrospective, cohort study using a regression ... -
The Brain And Exercise: In Sickness And In Health
( Frontiers Media , 2022 , Article)The brain, like any other organ in the body, is made up of various types of cells. Nerve cells called neurons are the major cells in the brain. Their main function is to transfer messages and orders to and from the organs ... -
Breast Cancer During Pregnancy: A Marked Propensity to Triple-Negative Phenotype.
( Frontiers Media , 2020 , Article)Breast and cervical cancers comprise 50% of all cancers during pregnancy. In particular, gestational breast cancer is considered one of the most aggressive types of cancers, which is a rare but fatal disease. However, the ... -
Breathing Clean Air: Navigating Indoor Air Purification Techniques and Finding the Ideal Solution
( MDPI , 2024 , Article)The prevalence of airborne pathogens in indoor environments presents significant health risks due to prolonged human occupancy. This review addresses diverse air purification systems to combat airborne pathogens and the ... -
Burden and disease pathogenesis of influenza and other respiratory viruses in diabetic patients
( Elsevier , 2022 , Article Review)Over the past two decades, diabetes mellitus (DM) has been receiving increasing attention among autoimmune diseases. The prevalence of type 1 and type 2 diabetes has increased rapidly and has become one of the leading ... -
Calreticulin regulates Src kinase in osteogenic differentiation from embryonic stem cells
( Elsevier , 2020 , Article)Calreticulin, the major Ca2+ buffer of the endoplasmic reticulum plays an important role in the choice of fate by embryonic stem cells. Using the embryoid body method of organogenesis, we showed impaired osteogenesis in ... -
Can commercial automated immunoassays be utilized to predict neutralizing antibodies after SARS-CoV-2 infection? A comparative study between three different assays.
( IMR , 2021 , Article)Background: High-throughput assays that can infer neutralizing activity against SARS-CoV-2 are of great importance for assessing the immunity induced by natural infection and COVID-19 vaccines. We aimed to evaluate the ... -
Cancer Metastasis: Dynamic Hetero-cellular Communications Between Cancer Cells and Host Tissues
( Springer International Publishing , 2023 , Book chapter)Metastasis is the most devastating aspect of cancer. Originally, tumor cells arise from a single clone, and then they undergo additional mutations and acquire invasive and metastatic features. These acquired mutations are ...
