Browsing Biomedical Research Center Research by Title
Now showing items 468-487 of 724
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Nano-Engineering in Traumatic Brain Injury
( Wiley , 2023 , Book chapter)Traumatic brain injury (TBI) is a leading cause of mortality and chronic disability worldwide TBI involves an initial primary phase triggered by an impactful force to the brain and a subsequent secondary pathological phase. ... -
Nanomedicine as a Potential Tool against Monkeypox.
( MDPI , 2023 , Article Review)Human monkeypox is a rare viral zoonosis that was first identified in 1970; since then, this infectious disease has been marked as endemic in central and western Africa. The disease has always been considered rare and ... -
Nanomedicine for Cancer.
( Bentham Science Publishers , 2022 , Other)Over the past decades, oncology has occupied the lion’s share of all nanomedical applications [1-3]. In 2020, up to 65% of the clinical trials involving nanomaterials were attending to cancer therapeutics and diagnostics ... -
Nanotechnology in medicine – our experiences
( Macedonian Pharmaceutical Association , 2022 , Article)The success of design criteria for long-circulating drug delivery systems to support membrane receptor-ligand interaction and internalization has been limited and there is a need to develop smarter approaches for efficient ... -
Nanotubes Impregnated Human Olfactory Bulb Neural Stem Cells Promote Neuronal Differentiation in Trimethyltin-induced Neurodegeneration Rat Model
( Wiley , 2017 , Article)Neural stem cells (NSCs) are multipotent self-renewing cells that could be used in cellular-based therapy for a wide variety of neurodegenerative diseases including Alzheimer's diseases (AD), Parkinson's disease (PD), ... -
Neutralizing antibodies against SARS-CoV-2 are higher but decline faster in mRNA vaccinees compared to individuals with natural infection.
( Oxford University Press , 2022 , Article)Waning protection against emerging SARS-CoV-2 variants by pre-existing antibodies elicited due to current vaccination or natural infection is a global concern. Whether this is due to the waning of immunity to SARS-COV-2 ... -
A New Deep Learning Method for Accurate Cardiac Heart Failure Prediction from RR Interval Measurements
( IEEE , 2022 , Conference Paper)cardiovascular diseases are the major cause of death worldwide. Early detection of heart failure will assist patients and medical professionals in taking better precautions to reduce risks. The objective of this study is ... -
A new One Health Framework in Qatar for future emerging and re-emerging zoonotic diseases preparedness and response
( Elsevier , 2023 , Article)One Health is increasingly recognized as an optimal approach to address the global risk of health threats originating at the human, animal, and ecosystem interface, and their impact. Qatar has successfully practiced One ... -
Nitric oxide releasing chitosan-poly (vinyl alcohol) hydrogel promotes angiogenesis in chick embryo model
( Elsevier B.V. , 2019 , Article)The lack of angiogenic activity is one of the serious complications of chronic wounds associated with delayed wound closure, chronic ulceration, and subsequent limb amputation. Multiple lines of evidence suggest that nitric ... -
Nitric Oxide Releasing Hydrogel Nanoparticles Decreases Epithelial Cell Injuries Associated With Airway Reopening
( Qatar University Press , 2021 , Poster)Introduction: Acute respiratory distress syndrome (ARDS) is an acute inflammatory lung condition. It is characterized by disruption of gas exchange inside the alveoli, accumulation of protein edema, and an increase in lung ... -
Nitric Oxide Releasing Hydrogel Nanoparticles Decreases Epithelial Cell Injuries Associated With Airway Reopening.
( Frontiers , 2021 , Article)Acute respiratory distress syndrome (ARDS) is an acute inflammatory lung condition. It is characterized by disruption of gas exchange inside the alveoli, accumulation of protein edema, and an increase in lung stiffness. ... -
Novel CD44-downstream signaling pathways mediating breast tumor invasion
( Ivyspring International Publisher , 2018 , Article Review)CD44, also known as homing cell adhesion molecule is a multi-structural cell molecule involved in cell-cell and cell-extracellular matrix communications. CD44 regulates a number of central signaling pathways, including ... -
A novel deep learning technique for morphology preserved fetal ECG extraction from mother ECG using 1D-CycleGAN
( Elsevier , 2024 , Article)The non-invasive fetal electrocardiogram (fECG) enables easy detection of developing heart abnormalities, leading to a significant reduction in infant mortality rate and post-natal complications. Due to the overlapping of ... -
A novel in ovo model to study cancer metastasis using chicken embryos and GFP expressing cancer cells.
( Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina , 2019 , Article)Cancer metastasis is the leading cause of cancer-related mortality worldwide. To date, several in vitro methodologies have been developed to understand the mechanisms of cancer metastasis and to screen various therapeutic ... -
Novel nitrogen-based chalcone analogs provoke substantial apoptosis in HER2-positive human breast cancer cells via JNK and ERK1/ERK2 signaling pathways
( MDPI , 2021 , Article)Natural chalcones possess antitumor properties and play a role as inducers of apoptosis, antioxidants and cytotoxic compounds. We recently reported that novel nitrogen chalcone-based compounds, which were generated in our ... -
Novel polymethoxylated chalcones as potential compounds against kras-mutant colorectal cancers
( Bentham Science Publishers , 2020 , Article)Background/Objective: KRAS-mutant colorectal cancers (CRC) are tumors that are associated with poor prognosis. However, no effective treatments are available to target them. Therefore, we designed and synthesized novel ... -
Novel Theileria sp. as an Etiology of Cutaneous Theileriosis among the Vulnerable Arabian Oryx
( MDPI , 2024 , Article)The Arabian Peninsula’s endemic ungulate, Oryx leucoryx, was on the verge of extinction at the end of the 1970s. Despite the different reintroduction programs, the International Union for Conservation of Nature is still ... -
Nox2 activity is required in obesity-mediated alteration of bone remodeling
( Hindawi Limited , 2018 , Article)Despite increasing evidence suggesting a role for NADPH oxidases (Nox) in bone pathophysiology, whether Nox enzymes contribute to obesity-mediated bone remodeling remains to be clearly elucidated. Nox2 is one of the ... -
Numerical Investigation of the Fetal Left Heart Hemodynamics During Gestational Stages
( Frontiers Media , 2021 , Article)Flow-driven hemodynamic forces on the cardiac tissues have critical importance, and have a significant role in the proper development of the heart. These mechanobiological mechanisms govern the cellular responses for the ... -
Oncolytic viruses as nanomedicines against the tumor microenvironment
( AMG Transcend Association , 2021 , Article Review)The tumor microenvironment is best described as the battleground for fighting cancer and the host immune system. Contrary to primitive beliefs that cancer growth and progression are solely dependent on cancer cells, recent ...
