Protection of natural infection against reinfection with SARS-CoV-2 JN.1 variant
Date
2024-05-01Author
Chemaitelly, HiamCoyle, Peter
Kacem, Mohamed Ali Ben
Ayoub, Houssein H.
Tang, Patrick
Hasan, Mohammad R.
Yassine, Hadi M.
Al Thani, Asmaa A.
Al-Kanaani, Zaina
Al-Kuwari, Einas
Jeremijenko, Andrew
Kaleeckal, Anvar H.
Latif, Ali N.
Shaik, Riyazuddin M.
Abdul-Rahim, Hanan F.
Nasrallah, Gheyath K.
Al-Kuwari, Mohamed Ghaith
Butt, Adeel A.
Al-Romaihi, Hamad E.
Al-Thani, Mohamed H.
Al-Khal, Abdullatif
Bertollini, Roberto
Abu-Raddad, Laith J.
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Metadata
Show full item recordAbstract
Evidence at the level of neutralizing antibodies suggests that the SARS-CoV-2 JN.1 variant demonstrates increased immune evasion compared to its parent lineage BA.2.86 and to recently circulating variants, such as XBB.1.5 and EG.5.1.1 JN.1 has also exhibited a growth advantage over other variants and triggered large SARS-CoV-2 waves in various countries,2 prompting the World Health Organization to classify it as a variant of interest on 19 December 2023.2 We estimated the effectiveness of natural infection in preventing reinfection with JN.1 during a large JN.1 wave in Qatar using the test-negative case-control study design.3,4
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