Browsing by Author "Zupin, Luisa"
Now showing items 1-19 of 19
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Bioactive Antimicrobial Peptides: A New Weapon to Counteract Zoonosis.
( MDPI , 2022 , Article Review)Zoonoses have recently become the center of attention of the general population and scientific community. Notably, more than 30 new human pathogens have been identified in the last 30 years, 75% of which can be classified ... -
Clinical–Epidemiological Characteristics and IFITM-3 (rs12252) Variant Involvement in HIV-1 Mother-to-Children Transmission Susceptibility in a Brazilian Population
( MDPI , 2023 , Article)Mother-to-children transmission (MTCT) is the main infection route for HIV-1 in children, and may occur during pregnancy, delivery, and/or postpartum. It is a multifactorial phenomenon, where genetic variants play an ... -
Comparison between nucleic acid amplification tests, antigen immunofluorescence assay, and in vitro infectivity in SARS-CoV-2 diagnosis.
( Springer , 2022 , Article)The number of SARS-CoV-2 detection tests requested to the laboratories has dramatically increased together with an urgent need to release reliable responses in a very short time. The two options taken into consideration ... -
Direct inactivation of SARS-CoV-2 by low level blue photobiomodulation LED at 470, 454 and 450 nm.
( Wiley , 2022 , Article)Blue light has been already reported as able to counteract different types of microorganisms including Gram-positive and Gram-negative bacteria, fungi and viruses, especially the enveloped ones. It has been reported that ... -
Effect of near-infrared and blue laser light on vero E6 cells SARS-CoV-2 infection model
( Wiley , 2022 , Article)Photobiomodulation therapy (PBMT) employing laser light has been emerging as a safe strategy to challenge viruses. In this study the effect of blue and near-infrared (NIR) laser light was assessed in an in vitro model of ... -
Effect of Short Time of SARS-CoV-2 Infection in Caco-2 Cells.
( MDPI , 2022 , Article)Coronavirus disease 19 (COVID-19) clinical manifestations include the involvement of the gastrointestinal tract, affecting around 10% of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected children. In ... -
Human Defensins from Antivirals to Vaccine Adjuvants: Rediscovery of the Innate Immunity Arsenal
( Bentham Science Publishers , 2022 , Article)Human defensins are a class of antimicrobial peptides, belonging to the innate immunity system. These peptides are expressed at the level of respiratory tract (both upper and lower) where they represent the first line of ... -
Impact of Sample Preparation Methods on Single-Cell X-ray Microscopy and Light Elemental Analysis Evaluated by Combined Low Energy X-ray Fluorescence, STXM and AFM
( MDPI , 2023 , Article)BACKGROUND: Although X-ray fluorescence microscopy is becoming a widely used technique for single-cell analysis, sample preparation for this microscopy remains one of the main challenges in obtaining optimal conditions for ... -
The mitochondrial-related effect of the 905 nm photobiomodulation therapy on 50B11 sensory neurons
( Wiley , 2023 , Article)Photobiomodulation therapy (PBMT) is known as a complementary tool to alleviate pain sensation in patients, nevertheless, there is still a gap of knowledge on its mechanism of action, thus limiting its clinical employment. ... -
Nanomedicine as a Potential Tool against Monkeypox.
( MDPI , 2023 , Article Review)Human monkeypox is a rare viral zoonosis that was first identified in 1970; since then, this infectious disease has been marked as endemic in central and western Africa. The disease has always been considered rare and ... -
Optimization of Anti-SARS-CoV-2 Treatments Based on Curcumin, Used Alone or Employed as a Photosensitizer.
( MDPI , 2022 , Article)Curcumin, the bioactive compound of the spice , has already been reported as a potential COVID-19 adjuvant treatment due to its immunomodulatory and anti-inflammatory properties. In this study, SARS-CoV-2 was challenged ... -
Paraviral cutaneous manifestations associated to SARS-CoV-2 Omicron variant
( Taylor and Francis Group , 2022 , Article)Background: The spreading of the SARS-CoV-2 Omicron variant is probably due to its increased transmissibility and ability to escape from neutralising antibodies. Cutaneous manifestations have been reported after infection ... -
SARS-CoV-2 does not replicate in HaCaT spontaneously immortalized human keratinocytes: implications for the pathogenesis of COVID-19-associated skin manifestations
( John Libbey Eurotext , 2022 , Article)Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)-related cutaneous manifestations have been reported [1], however, the direct or indirect role of SARS-CoV-2 infection in their pathophysiology is still debated ... -
SARS-CoV-2 modulates virus receptor expression in placenta and can induce trophoblast fusion, inflammation and endothelial permeability
( Frontiers Media , 2022 , Article)SARS-CoV-2 is a devastating virus that induces a range of immunopathological mechanisms including cytokine storm, apoptosis, inflammation and complement and coagulation pathway hyperactivation. However, how the infection ... -
SARS-CoV-2 RNA Recovery from Air Sampled on Quartz Fiber Filters: A Matter of Sample Preservation?
( MDPI , 2022 , Report)The airborne route of transmission of SARS-CoV-2 was confirmed by the World Health Organization in April 2021. There is an urge to establish standardized protocols for assessing the concentration of SARS-CoV-2 RNA in air ... -
Think like a Virus: Toward Improving Nanovaccine Development against SARS-CoV-2
( MDPI , 2022 , Article Review)There is no doubt that infectious diseases present global impact on the economy, society, health, mental state, and even political aspects, causing a long-lasting dent, and the situation will surely worsen if and when the ... -
Transient Receptor Potential Ankyrin 1 (TRPA1) Methylation and Chronic Pain: A Systematic Review
( MDPI , 2023 , Other)Background and Objective: Chronic pain represents a major global health issue in terms of psycho-physiological, therapeutic, and economic burden, not limited to adults but also to the pediatric age. Despite its great impact, ... -
Unraveling the Role of Sex Hormones on Keratinocyte Functions in Human Inflammatory Skin Diseases
( MDPI , 2022 , Article Review)The skin exerts several fundamental functions that are the first physical, chemical and immune barriers to the human body. Keratinocytes, the main cell type of the epidermis, provide mechanical defense, support skin integrity ... -
Upside-Down Preference in the Forskolin-Induced In Vitro Differentiation of 50B11 Sensory Neurons: A Morphological Investigation by Label-Free Non-Linear Microscopy.
( MDPI , 2023 , Article)In this study, we revealed a peculiar morphological feature of 50B11 nociceptive sensory neurons in in vitro culture related to the forskolin-induced differentiation of these cells growing upside-down on cover glass supports. ...
