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    F-box proteins in cancer stemness: An emerging prognostic and therapeutic target 

    Abdul Q., Khan; Al-Tamimi, Maha; Uddin, Shahab; Steinhoff, Martin ( Elsevier , 2021 , Article)
    Cancer is a complex heterogenic disease with significant therapeutic challenges. The presence of cancer stem cells (CSCs) in cancer tissue orchestrates tumor growth, progression, and metastasis, the tumor heterogeneity, ...

    Reactive oxygen species (ROS) in cancer pathogenesis and therapy: An update on the role of ROS in anticancer action of benzophenanthridine alkaloids 

    Abdul Q., Khan; Rashid, Khalid; AlAmodi, Abdulhadi A.; Agha, Maha Victor; Akhtar, Sabah; Hakeem, Ishrat; Raza, Syed Shadab; Uddin, Shahab... more authors ... less authors ( Elsevier , 2021 , Article)
    Reactive oxygen species play crucial role in biological homeostasis and pathogenesis of human diseases including cancer. In this line, now it has become evident that ROS level/concentration is a major factor in the growth, ...
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    The potential role of vitamin C in empowering cancer immunotherapy 

    Takwa, Bedhiafi; Inchakalody, Varghese Philipose; Fernandes, Queenie; Mestiri, Sarra; Billa, Nashiru; Uddin, Shahab; Merhi, Maysaloun; Dermime, Said... more authors ... less authors ( Elsevier , 2022 , Article)
    Vitamin C also known as L-ascorbic acid is a nutrient naturally occurring in many fruits and vegetables and widely known for its potent antioxidant activity. Several studies have highlighted the importance of using high ...
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    Molecular pathogenesis of Cutaneous T cell Lymphoma: Role of chemokines, cytokines, and dysregulated signaling pathways 

    Kalyani, Patil; Kuttikrishnan, Shilpa; Khan, Abdul Q.; Ahmad, Fareed; Alam, Majid; Buddenkotte, Joerg; Ahmad, Aamir; Steinhoff, Martin; Uddin, Shahab... more authors ... less authors ( Elsevier , 2022 , Article Review)
    Cutaneous T cell lymphomas (CTCLs) are a heterogeneous group of lymphoproliferative neoplasms that exhibit a wide spectrum of immune-phenotypical, clinical, and histopathological features. The biology of CTCL is complex ...
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    Treatment with decitabine induces the expression of stemness markers, PD-L1 and NY-ESO-1 in colorectal cancer: potential for combined chemoimmunotherapy 

    Taib, Nassiba; Merhi, Maysaloun; Inchakalody, Varghese; Mestiri, Sarra; Hydrose, Shereena; Makni-Maalej, Karama; Raza, Afsheen; Sahir, Fairooz; Azizi, Fouad; Nizamuddin, Parveen B.; Fernandes, Queenie; Yoosuf, Zeenath Safira K. M.; Almoghrabi, Salam; Al-Zaidan, Lobna; Shablak, Alaaeldin; Uddin, Shahab; Maccalli, Cristina; Al Homsi, Mohammed Ussama; Dermime, Said... more authors ... less authors ( BioMed Central Ltd , 2023 , Article)
    Background: The mechanism of tumor immune escape and progression in colorectal cancer (CRC) is widely investigated in-vitro to help understand and identify agents that might play a crucial role in response to treatment and ...
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    Epigenetic programing of cancer stemness by transcription factors-non-coding RNAs interactions 

    Alsayed, Reem Khaled M.E.; Sheikhan, Khalid Sultan A.M.; Alam, Majid Ali; Buddenkotte, Jorg; Steinhoff, Martin; Uddin, Shahab; Ahmad, Aamir... more authors ... less authors ( Elsevier , 2023 , Article Review)
    Cancer ‘stemness’ is fundamental to cancer existence. It defines the ability of cancer cells to indefinitely perpetuate as well as differentiate. Cancer stem cell populations within a growing tumor also help evade the ...
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    Bioinformatics Analysis Reveals FOXM1/BUB1B Signaling Pathway as a Key Target of Neosetophomone B in Human Leukemic Cells: A Gene Network-Based Microarray Analysis 

    Kuttikrishnan, Shilpa; Masoodi, Tariq; Sher, Gulab; Bhat, Ajaz A.; Patil, Kalyani; El-Elimat, Tamam; Oberlies, Nicholas H.; Pearce, Cedric J.; Haris, Mohmmad; Ahmad, Aamir; Alali, Feras Q.; Uddin, Shahab... more authors ... less authors ( Frontiers Media S.A. , 2022 , Article)
    Abnormal expression of Forkhead box protein M1 (FOXM1) and serine/threonine kinase Budding uninhibited by benzimidazoles 1 (BUB1B) contributes to the development and progression of several cancers, including chronic ...
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    Anticancer activity of Neosetophomone B by targeting AKT/SKP2/MTH1 axis in leukemic cells 

    Kuttikrishnan, Shilpa; Bhat, Ajaz A.; Mateo, Jericha M.; Ahmad, Fareed; Alali, Feras Q.; El-Elimat, Tamam; Oberlies, Nicholas H.; Pearce, Cedric J.; Uddin, Shahab... more authors ... less authors ( Elsevier , 2022 , Article)
    Neosetophomone B (NSP–B), a meroterpenoid fungal secondary metabolite, was investigated for its anticancer potential in leukemic cell lines (K562 and U937). NSP-B treatment of leukemic cells suppressed cell viability by ...
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    Applications of polydopaminic nanomaterials in mucosal drug delivery 

    Takwa, Bedhiafi; Idoudi, Sourour; Alhams, Areej Ali; Fernandes, Queenie; Iqbal, Heba; Basineni, Renuka; Uddin, Shahab; Dermime, Said; Merhi, Maysaloun; Billa, Nashiru... more authors ... less authors ( Elsevier , 2023 , Article Review)
    Polydopamine (PDA) is a biopolymer with unique physicochemical properties, including free-radical scavenging, high photothermal conversion efficiency, biocompatibility, biodegradability, excellent fluorescent and theranostic ...
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    Liquid biopsy: a step closer to transform diagnosis, prognosis and future of cancer treatments 

    Lone, Saife N.; Nisar, Sabah; Masoodi, Tariq; Singh, Mayank; Rizwan, Arshi; Hashem, Sheema; El-Rifai, Wael; Bedognetti, Davide; Batra, Surinder K.; Haris, Mohammad; Bhat, Ajaz A.; Macha, Muzafar A.... more authors ... less authors ( BMC , 2022 , Article Review)
    Over the past decade, invasive techniques for diagnosing and monitoring cancers are slowly being replaced by non-invasive methods such as liquid biopsy. Liquid biopsies have drastically revolutionized the field of clinical ...
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      Uddin, Shahab (65) Crovella, Sergio (37) Haris, Mohammad (35) Kuttikrishnan, Shilpa (23) ... View More
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      Article (82) Article Review (52) Poster (17) Book chapter (4) Conference (1) Presentation (1) Report (1)
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      Cancer (10) Apoptosis (9) Cancer stem cells (8) Drug resistance (8) ... View More
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      2020 - 2025 (124) 2010 - 2019 (33) 2008 - 2009 (1)
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